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ProteomicsAdaptive lab evolution and omics characterization enable tolerance engineering of Pseudomonas putida KT2440 to produce the jet-fuel precursor isoprenol
Pseudomonas putida KT2440 (KT2440) has been established as an industrially relevant chassis for the production of the jetfuel precursor isoprenol. However, this strain assimilated isoprenol as sole carbon source and also showed impaired growth at isoprenol concentrations > 2 g/L which is a significa...
ORGANISM(S): Pseudomonas putida KT2440 
2025-05-28 | PXD054609 | Pride
Pseudomonas putida Sustainable aviation fuel Isoprenol Adaptive laboratory evolution Tolerance engineering 
ProteomicsSimultaneous Optimization of Multi-lignocellulosic-sugar Catabolism via Systematic Laboratory Evolution in Dynamic Conditions
The development of microbial bioproduction is challenged by the complexity and variability of industrial feedstocks. This study aimed to systematically and simultaneously optimize catabolism of multiple sugars present in common renewable lignocellulose by adaptive laboratory evolution (ALE) using dy...
ORGANISM(S): Pseudomonas putida KT2440 
2026-06-29 | PXD055215 | Pride
Pseudomonas putida Adaptive laboratory evolution (ale) Proteomics Lignocellulose 
ProteomicsCell line xenograft experiment
Pediatric ALL cell line 380 was injected via tail vein into NSG mice. Triplicate 380 cell samples were also prepared at the timepoint of injection and stored at -80 oC for comparative analysis with CDXs. Mice were euthanized at onset of leukemia symptoms and spleen, bone marrow and liver samples wer...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-01-20 | MSV000086727 | MassIVE
ProteomicsGlobal protein analysis of pediatric acute leukemia patients and matched xenografts
Proteomics reveal protein stability after xenotransplantation in murine models. Tryptic peptide digests from patient mononuclear cells were analyzed by Data Independent Acquisition (DIA) mass spectrometry. High-pH fractionation was performed on a pool of samples, followed by data dependent acquisiti...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-12-02 | MSV000084646 | MassIVE
ProteomicsPhosphoproteome analysis of pediatric acute leukemia patients and matched xenografts
Proteomics reveal PTM stability after xenotransplantation in murine models. Phosphopeptides enriched using magnetic FeNTA beads were analyzed by Data Independent Acquisition (DIA) mass spectrometry. High-pH fractionation was performed on a pool of samples, followed by data dependent acquisition (DDA...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-12-02 | MSV000084645 | MassIVE
ProteomicsN terminome analysis of pediatric acute leukemia patients and matched xenografts
Proteomics reveal PTM stability after xenotransplantation in murine models. N termini enriched using HUNTER technique were analyzed by Data Independent Acquisition (DIA) mass spectrometry. High-pH fractionation was performed on a pool of samples, followed by data dependent acquisition (DDA) mass spe...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-12-02 | MSV000084643 | MassIVE
UnknownSurgical treatment of refractory low back pain using implanted BurstDR spinal cord stimulation (SCS) in a cohort of patients without options for corrective surgery: Findings and results from the DISTINCT study, a prospective randomized multi-center-controlled trial.
Not available
S-EPMC11321325 | biostudies-literature
TranscriptomicsExpression of Intergenic Clusters
Contains a row for each intergenic cluster in each sample, indicating whether our analysis called the cluster "present" or "absent" in the sample. Intergenic clusters are novel (unannotated) genes detected by aligning Arabidopsis cDNAs/ESTs to the genome. Cluster coordinates refer to version 3 of th...
ORGANISM(S): Arabidopsis thaliana 
2010-06-05 | E-GEOD-638 | biostudies-arrayexpress
TranscriptomicsExpression of Annotated Genes
Contains a row for each annotated gene in each sample, indicating whether our analysis called the gene "present" or "absent" in the sample. Gene names and coordinates refer to version 3 of the TIGR annotation as submitted to GenBank (GI numbers 22330780, 22326553, 22331929, 22329272, 22328163).
ORGANISM(S): Arabidopsis thaliana 
2010-06-05 | E-GEOD-636 | biostudies-arrayexpress
TranscriptomicsAntisense Expression of Annotated Genes
Contains a row for each annotated gene in each sample, indicating whether our analysis called the region antisense to the coding region of the gene "present" or "absent" in the sample. Gene names and coordinates refer to version 3 of the TIGR annotation as submitted to GenBank (GI numbers 22330780, ...
ORGANISM(S): Arabidopsis thaliana 
2010-06-05 | E-GEOD-637 | biostudies-arrayexpress
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