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TranscriptomicsHypoxia-induced modulation of gene expression in human adipocytes - A microarray study
Obesity is characterised by expansion of white adipose tissue, accompanied by an inflamatory response. It has been proposed that the inflammatory state observed may be linked to relative hypoxia in clusters of adipocytes distant from vasculature. Adipose tissue hypoxia has been observed in both an...
ORGANISM(S): Homo sapiens 
2012-03-09 | E-GEOD-34007 | biostudies-arrayexpress
MetabolomicsPRDM15 is a master regulator of metabolism essential to sustain B-cell lymphomagenesis
PRDM family members are sequence-specific transcriptional regulators involved in cell identity and fate determination and are often dysregulated in cancer. The PRDM15 gene is of particular interest, given its relatively low expression in adult tissues and its overexpression in follicular lymphomas (...
2025-06-16 | MTBLS1639 | MetaboLights
UnknownAtezolizumab and bevacizumab, with or without radiotherapy, versus docetaxel in patients with metastatic non-small cell lung cancer previously treated with a checkpoint inhibitor and chemotherapy: results from the randomized, phase Ib/II MORPHEUS-Lung study.
Not available
S-EPMC12323520 | biostudies-literature
TranscriptomicsMicroarray Analysis of Genes Regulated by Macrophage-Conditioned Media Treatment of Human Pre-Adipocytes
A major development in the study of obesity is the recognition that the condition is characterised by chronic mild inflammation. Within adipose tissue, this involves the infiltration of macrophages, as well as the direct inflammatory response of the adipocytes and pre-adipocytes. This study has us...
ORGANISM(S): Homo sapiens 
2011-12-21 | E-GEOD-27503 | biostudies-arrayexpress
UnknownAssessing early child development and its association with stunting and schistosome infections in rural Zimbabwean children using the Griffiths Scales of Child Development.
Not available
S-EPMC8357151 | biostudies-literature
UnknownComplications and Revision Rates in Minimally Invasive Robotic-Guided Versus Fluoroscopic-Guided Spinal Fusions: The MIS ReFRESH Prospective Comparative Study.
Not available
S-EPMC8565511 | biostudies-literature
GenomicsGenome-wide binding profiles of KLF3 and KLF3 mutants in MEF cells
Transcription factors are often regarded as being comprised of a DNA-binding domain and a functional domain. The two domains are considered separable and autonomous, with the DNA-binding domain directing the factor to its target genes and the functional domain imparting transcriptional regulation. W...
ORGANISM(S): Mus musculus 
2013-10-17 | E-GEOD-44748 | biostudies-arrayexpress
UnknownNear-infrared spectroscopy as a high-throughput phenotyping method for fusiform rust resistance in loblolly pine.
Not available
S-EPMC12710050 | biostudies-literature
TranscriptomicsActivity of a stem cell enhancer influences stem cell programs and clinical outcome in leukaemia
Chip-chip data from primary human AML patient blasts, normal CD34+ HSCs, normal neutrophils and normal T cells with H3K9 and H3K27 antibodies. Gene expression profiling from primary human AML patient blasts and CD34+ normal cells. Analysis of the chromatin landscape of the ERG locus using H3K9 and H...
ORGANISM(S): Homo sapiens 
2013-04-04 | E-GEOD-38865 | biostudies-arrayexpress
UnknownThe LMO2-LDB1-TAL1 complex regulates transcription networks in acute myeloid leukemia.
Not available
S-EPMC12835595 | biostudies-literature
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