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TranscriptomicsIsl1-Lhx3 fusion specifies motor neuron fate by inducing motor neuron genes and concomitantly suppressing the interneuron programs
Combinatorial transcription codes generate the myriad of cell types during development, and thus likely provide crucial insights into directed differentiation of stem cells to a specific cell type. The LIM-complex composed of Isl1 and Lhx3 directs the specification of spinal motor neurons (MNs) in e...
ORGANISM(S): Mus musculus 
2012-02-03 | E-GEOD-35510 | biostudies-arrayexpress
TranscriptomicsGene expression regulation by C. elegans SAM-10
Little is known about transcriptional control of neurite branching or presynaptic differentiation, events that occur relatively late in neuronal development. Using the C. elegans mechanosensory circuit as an in vivo model, we show that SAM-10, an ortholog of mammalian Single-Stranded DNA binding P...
ORGANISM(S): Caenorhabditis elegans 
2010-11-12 | E-GEOD-25285 | biostudies-arrayexpress
UnknownUnveiling the molecular basis of selective fluorination of SAM-dependent fluorinases.
Not available
S-EPMC12080486 | biostudies-literature
UnknownRiboswitches that sense S-adenosylhomocysteine and activate genes involved in coenzyme recycling.
Not available
S-EPMC2712820 | biostudies-literature
TranscriptomicsSenescent and myofibroblastic cancer-associated fibroblasts share a contractile phenotype regulated by NOX4 generation of reactive oxygen species in the tumour microenvironment
Cancer associated fibroblasts characterized by an myofibroblastic phenotype play a major role in the tumour microenvironment, being associated with poor prognosis. We found that this cell population is made in part by senescent fibroblasts in vivo. As senescent fibroblasts and myofibroblasts have be...
ORGANISM(S): Homo sapiens 
2017-06-01 | E-MTAB-3101 | biostudies-arrayexpress
TranscriptomicsFetal lung development
Fetal lung development is a complex biological process, which involves temporal and spatial regulations of many genes. To understand molecular mechanisms of this process, we investigated gene expression profiling of lungs at gestational day 18, 19, 20, 21, new born, and adult rats using in-house rat...
ORGANISM(S): Rattus norvegicus 
2010-07-01 | E-GEOD-3302 | biostudies-arrayexpress
UnknownEvidence for a second class of S-adenosylmethionine riboswitches and other regulatory RNA motifs in alpha-proteobacteria.
Not available
S-EPMC1273637 | biostudies-literature
UnknownS-adenosyl methionine synthetase SAMS-5 mediates dietary restriction-induced longevity in Caenorhabditis elegans.
Not available
S-EPMC7657561 | biostudies-literature
UnknownEffect of SAM-Dependent Methyltransferases from <i>Halomonas</i> sp. YLGW01 on Phospholipid Fatty Acids Composition and Production of Polyhydroxalkanoates in <i>Escherichia coli</i>.
Not available
S-EPMC12089945 | biostudies-literature
UnknownPopulation Structure and Genetic Diversity of Italian Beef Breeds as a Tool for Planning Conservation and Selection Strategies.
Not available
S-EPMC6912484 | biostudies-literature
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