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TranscriptomicsEvolution and Pathogenic Mechanism of Rice Sheath Blight Pathogen
Analysis of RNA expression of Rhizoctonia solani AG1 IA. mRNA-seq of R. solani AG1 IA at 6 timepoints during the plant infection were sequenced. Cufflinks was used for calculating expected fragments per kilobase of transcript per million fragments sequenced (FPKM) values. Expression and regulation w...
ORGANISM(S): Rhizoctonia solani AG-1 IA 
2013-01-28 | E-GEOD-32577 | biostudies-arrayexpress
ProteomicsThe novel type II toxin-antitoxin PacTA modulates Pseudomonas aeruginosa iron homeostasis by obstructing the DNA-binding activity of Fur
Type II Toxin-antitoxin (TA) systems are widely distributed in bacterial and archaeal genomes with diverse critical cellular functions such as defense against phages, biofilm formation, persistence and virulence. GCN5-related N -acetyltransferase (GNAT) toxin, with an acetyltransferase activity-dep...
ORGANISM(S): Pseudomonas Aeruginosa Pa14 
2022-05-05 | PXD033699 |
TranscriptomicsExpression profiling reveals novel pathways in the transformation of melanocytes to melanomas. II
Spotted oligonucleotide microarrays were used to assess global differential gene expression comparing normal human melanocytes with six independent melanoma cell strains from advanced lesions. The data, validated at the protein level for selected genes, confirmed the overexpression in melanoma cells...
ORGANISM(S): Homo sapiens 
2010-07-01 | E-GEOD-4576 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of normal human melanocytes and melanoma cell lines from advanced lesions
Affymetrix oligonucleotide microarrays were used to assess global differential gene expression comparing normal human melanocytes with six independent melanoma cell strains from advanced lesions. The data, validated at the protein level for selected genes, confirmed the overexpression in melanoma ce...
ORGANISM(S): Homo sapiens 
2007-06-22 | E-GEOD-4570 | biostudies-arrayexpress
ProteomicsA Recombinant Vaccine Targeting Receptor-binding Domain of SARS-CoV-2 Spike Protein Induces Protective Immunity in Mice and Non-human Primates
The novel Coronavirus SARS-CoV-2 causes a respiratory illness called COVID-19 leading to a pandemic. An effective preventive vaccine against this virus is urgently needed.
ORGANISM(S): Severe Acute Respiratory Syndrome Coronavirus 2 
PXD020653 |
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