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TranscriptomicsComparison of glioblastoma tissue, glioblastoma primary culture, and normal brain
Pooled samples of primary GBM tissues, primary cultures, and normal tissues were analyzed by MPSS. 2 Samples
ORGANISM(S): Homo sapiens 
2010-05-06 | E-GEOD-14878 | biostudies-arrayexpress
TranscriptomicsGenes regulated by UCHL1 in ovarian cancer cells
UCHL1 is related to apoptosis and proliferation in cancers and we sought to identify genes regulated by UCHL1 UCHL1 was knocked down in A2780 (A2780-shUCHL1). A2780-shUCHL1 and A2780-control were cultured in RPMI and total RNA was extracted and hybridizated on Affymetrix.GeneChip.HG-U133_Plus_2
ORGANISM(S): Homo sapiens 
2013-01-30 | E-GEOD-43884 | biostudies-arrayexpress
TranscriptomicsGenes regulated by Sox2 in glioma cancer cell line
Knockdown of Sox2 in LN229 gliomal cancer cells decrease their growth rates in vitro. We used microarrays to detail the global programme of gene expression in Sox2 Knockdown LN229 cells compared with mock knockdown LN229 cells Sox2 knockdown LN229 cells and and mock knockdown LN229 cells were cultur...
ORGANISM(S): Homo sapiens 
2011-01-10 | E-GEOD-23838 | biostudies-arrayexpress
GenomicsChip-Seq analysis of Sox2 protein genome-wide DNA binding sites in glioma cancer cells
We report here our results of the genome wide target identification of SOX2 in GBM cells by ChIP-seq analysis. Identification of Sox2 DNA binding site in glioma cancer cells
ORGANISM(S): Homo sapiens 
2011-01-10 | E-GEOD-23795 | biostudies-arrayexpress
GenomicsGenome-wide maps of methylation state in cisplatin sensitive and resistant ovarian cancer cell line
We report the application of methyl-binding protein sequencing (MBD-seq) to global identify aberrant methylation between cisplatin sensitive and resistant ovarian cancer cell lines Detection of aberrant methylation states between cisplatin sensitive and resistant cell lines
ORGANISM(S): Homo sapiens 
2012-04-10 | E-GEOD-31418 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human PC3 cells transfected with androgen receptor treated with various concentration of androgens
We compared PC3 cells with or without harboring the wild-AR construct in the growth conditions of 1nM R1881, 10nM R1881 and ethanol (the solvent for R1881). The MOCK control is PC3 cells transfected with the empty vectors. Experiment Overall Design: 2 PC3 Samples transfected with empty vector, witho...
ORGANISM(S): Homo sapiens 
2009-03-15 | E-GEOD-15091 | biostudies-arrayexpress
TranscriptomicsGenes regulated by Sox2 in colorectal cancer cell line
Knockdown of Sox2 in SW620 colorectal cancer cells decrease their growth rates in vitro and in vivo in xenograft models. We used microarrays to detail the global programme of gene expression in Sox2 Knockdown sw620 cells compared with mock knockdown sw620 cells Sox2 knockdown sw620 cells and and moc...
ORGANISM(S): Homo sapiens 
2011-03-01 | E-GEOD-20689 | biostudies-arrayexpress
TranscriptomicsGenes regulated by has-mir-31 in glioma cell line
Overexpression of miR-31 inhibits the migration and invasion ability of glioma cell. We sought to obtain the genes regulated by mir-31 in glioma cell line. The gene expression of U251-mir-31 (U251 over expressing mir-31) and U251-control. U251-Control and U251-mir-31 cells were cultured in DMEM cell...
ORGANISM(S): Homo sapiens 
2012-09-01 | E-GEOD-28810 | biostudies-arrayexpress
GenomicsSOX4 genome binding targets in glioblastoma cell line
Overexpression of SOX4 in LN229 glioblastoma cells prevents their cell cycle Examination of SOX4 binding profile in prostate cell LN229-SOX4 with LN229-GFP as negative control.
ORGANISM(S): Homo sapiens 
2014-10-20 | E-GEOD-51663 | biostudies-arrayexpress
TranscriptomicsGenes regulated by SOX4 in glioblastoma cell line
Overexpression of SOX4 in LN229 glioblastoma cells prevents their cell cycle We used microarrays to detail the global programme of gene expression in SOX4 overexpression LN229 cells compared with mock control LN229 cells SOX4 overexpression LN229 cells and and control LN229 cells were cultured in DM...
ORGANISM(S): Homo sapiens 
2014-09-30 | E-GEOD-51301 | biostudies-arrayexpress
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