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TranscriptomicsRNA-seq of Procr-expressing mouse mammary myoepithelium
Procr, also known as EPCR, is a protein C receptor known to function in the platelet coagulation cascade. We have used RNA-seq to examine RNA differential expression between Procr+ and Procr- myoepithelium in mouse mammary gland. Examine RNA differential expression among subsets of freshly sorted mo...
ORGANISM(S): Mus musculus 
2014-10-31 | E-GEOD-58088 | biostudies-arrayexpress
UnknownCNP signal pathway up-regulated in rectum of depressed rats and the interventional effect of Xiaoyaosan.
Not available
S-EPMC4316094 | biostudies-literature
TranscriptomicsMicroarray of 3D cultured basal cells in the presence of Wnt3A
Adult stem cells have the ability to self-renew and to generate specialized cells. Self-renewal is dependent on extrinsic niche factors but few of those signals have been identified. We show that adult mammary glands contain a Wnt-responsive cell population that is enriched for stem cells. In cell c...
ORGANISM(S): Mus musculus 
2014-10-22 | E-GEOD-55117 | biostudies-arrayexpress
TranscriptomicsmiRNA expression profile analysis of Clonorchis sinensis by Solexa deep sequencing
Clonorchis sinensis is a zoonotic parasite causing clonorchiasis associated with human diseases such as biliary calculi, cholecystitis, liver cirrhosis, and is classified as carcinogenic to humans for cholangiocarcinoma. MicroRNAs (miRNAs) are non-coding, regulating small RNA molecules essential for...
ORGANISM(S): Clonorchis sinensis 
2010-09-03 | E-GEOD-22244 | biostudies-arrayexpress
ProteomicsDirected natural evolution generates a next-generation oncolytic virus with a high potency and safety profile for multiple solid tumors
Mass spectrometry raw data for submitting manuscript entitled "Directed natural evolution generates a next-generation oncolytic virus with a high potency and safety profile for multiple solid tumors" to Nature Communications.
ORGANISM(S): Homo sapiens (Human) 
2023-05-22 | PXD037429 | Pride
Oncolytic virus m1 
UnknownN-acetyltransferase 10 affects the proliferation of intrahepatic cholangiocarcinoma and M2-type polarization of macrophages by regulating C-C motif chemokine ligand 2.
Not available
S-EPMC11440763 | biostudies-literature
UnknownReduction of C-reactive protein, low-density lipoprotein cholesterol, and its relationship with cardiovascular events of different lipid-lowering therapies: A systematic review and meta-analysis of randomized controlled trials.
Not available
S-EPMC9478215 | biostudies-literature
MetabolomicsA polyamine-centric blood-based metabolite panel predictive of poor response to CAR T-cell therapy in large B cell lymphoma

Anti-CD19 chimeric antigen receptor (CAR) T-cell therapy for relapsed or refractory (r/r) large B-cell lymphoma (LBCL) results in durable response in only a subset of patients. MYC overexpression in LBCL tumors is associated with poor response to treatment. We tested whether a MYC-driven polyamin...

2022-10-31 | MTBLS5381 | MetaboLights
MetabolomicsDifferent regions of synaptic vesicle membrane regulate VAMP2 conformation for the SNARE assembly
Vesicle associated membrane protein 2 (VAMP2/synaptobrevin2), a core SNARE protein residing on synaptic vesicles (SVs), forms helix bundles with syntaxin-1 and SNAP25 for the SNARE assembly. Prior to the SNARE assembly, the structure of VAMP2 is unclear. Here, by using in-cell NMR spectroscopy, we d...
2021-10-06 | MTBLS1503 | MetaboLights
UnknownStabilised frequency of extreme positive Indian Ocean Dipole under 1.5 °C warming.
Not available
S-EPMC5897553 | biostudies-literature
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