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Unknown(11R,13R)-13-(Tetra-lin-1-ylamino)-4,5-ep-oxy-11,13-dihydro-costunolide.
Not available
S-EPMC2960798 | biostudies-literature
UnknownA Human Lin- CD123+ CD127low Population Endowed with ILC Features and Migratory Capabilities Contributes to Immunopathological Hallmarks of Psoriasis.
Not available
S-EPMC5332395 | biostudies-literature
TranscriptomicsLIN28 binds messenger RNAs at GGAGA motifs and regulates splicing factor abundance (HTS)
LIN28 is a conserved RNA binding protein implicated in pluripotency, reprogramming and oncogenesis. Previously shown to act primarily by blocking let-7 microRNA (miRNA) biogenesis, here we elucidate distinct roles of LIN28 regulation via its direct messenger RNA (mRNA) targets. Through cross-linking...
ORGANISM(S): Homo sapiens 
2012-09-10 | E-GEOD-39872 | biostudies-arrayexpress
TranscriptomicsBulk RNAseq of megakaryocytes and Lin- cells of mice with Srsf2-P95H mutation, Jak2-V617F mutation, both, or none
We performed bulk RNAseq of sorted megakaryocytes and subsequent Lin- cells to study the impact of the combination of Jak2 V617F mutations and Srsf2 P95H mutations
ORGANISM(S): Mus musculus 
2023-07-01 | E-MTAB-11960 | biostudies-arrayexpress
TranscriptomicsRNA-seq of mouse adipose stem and progenitor cells
Population control for the scRNA-seq based analysis a well-established fraction of mouse subcutaneous adipose-derived stromal vascular fraction (SVF) cells that is generally considered to harbour adipogenic stem and progenitor cells (ASPCs). We collected Lin- (CD31- CD45- TER119-) CD29+ CD34+ SCA1+ ...
ORGANISM(S): Mus musculus 
2018-05-01 | E-MTAB-5818 | biostudies-arrayexpress
ProteomicsThe EN-TEx Resource for Personal Functional Genomics
An overall goal of functional genomics has been to measure the impact of variants on molecular endophenotypes (e.g. gene expression levels or the degree of TF binding) and relate this to organismal traits and disease phenotypes. However, all the experiments to date have been described relative to a ...
ORGANISM(S): Homo sapiens (Human) 
2024-05-22 | PXD022787 | Pride
Personal genomics Tmt Human Proteogenomics Tissue En-tex 
TranscriptomicsCoculture with lin-/c-kit+ Stem Cells leads to a Paracrine Mediated Inhibition of Apoptosis in Cardiomyocytes
Background: Experimental studies have suggested that stem cells (SC) may exert their beneficial effects on the ischemic heart by paracrine activation of antiapoptotic pathways. In order to identify potential cardioprotective mediators, we performed a systematic analysis of the differential gene expr...
ORGANISM(S): Mus musculus 
2012-06-18 | E-GEOD-21098 | biostudies-arrayexpress
TranscriptomicsLIN28 binds messenger RNAs at GGAGA motifs and regulates splicing factor abundance
This SuperSeries is composed of the following subset Series: GSE39855: LIN28 binds messenger RNAs at GGAGA motifs and regulates splicing factor abundance (splicing array) GSE39872: LIN28 binds messenger RNAs at GGAGA motifs and regulates splicing factor abundance (HTS) Refer to individual Series
ORGANISM(S): Homo sapiens 
2012-09-10 | E-GEOD-39873 | biostudies-arrayexpress
TranscriptomicsA mouse model of deregulation of the malt1 oncogene recapitulates the pathogenesis of human malt lymphoma [MouseSca1 dataset]
Attempts at modeling chromosomal translocations involving MALT1 gene, hallmarks of human mucosa-associated lymphoid tissue (MALT) lymphoma, have failed to reproduce the disease in mice. Here we describe a transgenic model in which MALT1 expression was targeted to mouse hematopoietic stem/progenitor ...
ORGANISM(S): Mus musculus 
2012-07-09 | E-GEOD-25636 | biostudies-arrayexpress
Transcriptomics3’RNA-seq of murine post-differentiation CD142− ASPCs treated with retinoic acid (RA)
To study the impact of retinoic acid treatment on the transcriptome of CD142− ASPCs, we performed bulk RNA-seq on CD142− ASPCs treated with different RA concentrations ranging between 0.01 to 100 μM, with 100 ng/ml of BSA (negative control), DMSO (negative control) or 100 ng/ml of EGF (positive cont...
ORGANISM(S): Mus musculus 
2021-06-26 | E-MTAB-10184 | biostudies-arrayexpress
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