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UnknownModels to Predict Hepatitis B Virus Infection Among Patients With Cancer Undergoing Systemic Anticancer Therapy: A Prospective Cohort Study.
Not available
S-EPMC7351320 | biostudies-literature
UnknownImpact of EML4-ALK Variant on Resistance Mechanisms and Clinical Outcomes in ALK-Positive Lung Cancer.
Not available
S-EPMC5903999 | biostudies-literature
UnknownWater and ion channels: crucial in the initiation and progression of apoptosis in central nervous system?
Not available
S-EPMC2647147 | biostudies-literature
TranscriptomicsComparison of gene expression between wild type, Notch1-activated, and RBPJ loss-of-function embryonic mouse yolk sac tissue at E9.5
The signaling cascades that direct the morphological differentiation of the vascular system during early embryogenesis are not well defined. To further understand the role of Notch signaling during endothelial differentiation, this study uses both an in vivo gain-of-function and in vivo loss-of-fun...
ORGANISM(S): Mus musculus 
2010-07-07 | E-GEOD-22418 | biostudies-arrayexpress
GenomicGWAS of Preterm Birth

Preterm birth (PTB, born before 37 weeks of gestation) is a leading cause of neonatal mortality and post-natal morbidity. PTB affects one in nine all live births in the U.S. Notably, the highest rate of PTB occurs among African Americans (one in six). PTB is a complex trait, likely determined by ...

phs000332 | dbGaP
GenomicsPi3kcb links Hippo-YAP and PI3K-AKT signaling pathways to promote cardiomyocyte proliferation and survival [ChIPseq]
Background—YAP, the nuclear effector of Hippo signaling, regulates cellular growth and survival in multiple organs, including the heart, by interacting with TEAD sequence specific DNA-binding proteins. Recent studies showed that YAP stimulates cardiomyocyte proliferation and survival. However, the d...
ORGANISM(S): Mus musculus 
2015-02-20 | E-GEOD-57717 | biostudies-arrayexpress
TranscriptomicsCircadian rhythm in clock mutants
One hundred ninety wildtype male C57BL/6J mice age 7-10 weeks were purchased from Jackson Laboratory and entrained to a 12:12 light:dark cycle for 2 weeks. Mice were placed in light-tight boxes on a 12:12 LD cycle for 4 weeks, then released into constant darkness. Starting 30 hours after entry into ...
ORGANISM(S): Mus musculus 
2010-06-12 | E-GEOD-3751 | biostudies-arrayexpress
ProteomicsSoluble SORLA enhances neurite outgrowth and regeneration through activation of EGFR and MAPK pathways
SORLA is a type I transmembrane component associated with Alzheimers disease (AD) risk. Although SORLA is abundantly expressed in neurons, physiological roles for SORLA remain yet unclear. Here, we show that cultured neurons overexpressing SORLA (SORLA TG) feature enhanced neurite length, and accele...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2020-05-12 | MSV000085400 | MassIVE
TranscriptomicsCircadian skeletal muscle_wt and Clock mutants
One hundred ninety wildtype male C57BL/6J mice age 7-10 weeks were purchased from Jackson Laboratory and entrained to a 12:12 light:dark cycle for 2 weeks. Mice were placed in light-tight boxes on a 12:12 LD cycle for 4 weeks, then released into constant darkness. Starting 30 hours after entry into ...
ORGANISM(S): Mus musculus 
2010-06-11 | E-GEOD-3746 | biostudies-arrayexpress
MetabolomicsImmunomodulatory fecal metabolites are associated with mortality in COVID-19 patients with respiratory failure
Respiratory failure and mortality from COVID-19 result from virus- and inflammation-induced lung tissue damage. The intestinal microbiome and associated metabolites are implicated in immune responses to respiratory viral infections, however their impact on progression of severe COVID-19 remains uncl...
2023-05-02 | MTBLS5288 | MetaboLights
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