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TranscriptomicsGenome-wide analysis of gene expression in MLL translocation transformed mouse leukemia cell lines
The purpose of this study is to investigate the transcriptional programs as it relates to disease latency initiated by different MLL fusion proteins, including: MLL-AF1p, MLL-AF6, MLL-Gas7, MLL-AF9 and MLL-ENL. Leukemia cell lines were established by transforming kit+ mouse bone marrow cells with re...
ORGANISM(S): Mus musculus 
2016-07-07 | E-GEOD-73457 | biostudies-arrayexpress
TranscriptomicsMyeloid derived suppressor cells enhance stemness of cancer cells by inducing miRNA101 and suppressing the corepressor CtBP2
The work identifies an immune associated cellular, molecular and clinical network involving MDSCs-microRNA101-CtBP2-stem cell core genes, which extrinsically controls cancer stemness and impacts patient outcome. Primary ovarian cancer cells (5 x105) were co-cultured with freshly sorted ovarian cance...
ORGANISM(S): Homo sapiens 
2013-08-23 | E-GEOD-50082 | biostudies-arrayexpress
TranscriptomicsWhole genome expression data from pre-auricular and post-auricular skin tissues
Photoaging is cumulative damage that is caused by chronic, repeated solar radiation exposure to skin. Its molecular mechanisms are poorly understood at the level of global gene expression.This study set out to uncover genes and functional modules involved in photoaging at the level of transcription,...
ORGANISM(S): Homo sapiens 
2014-02-07 | E-GEOD-38308 | biostudies-arrayexpress
UnknownA Phase II Study of Atezolizumab, Pertuzumab, and High-Dose Trastuzumab for Central Nervous System Metastases in Patients with HER2-Positive Breast Cancer.
Not available
S-EPMC11528201 | biostudies-literature
UnknownMultiomics reveals microbial metabolites as key actors in intestinal fibrosis in Crohn's disease
Not available
S-SCDT-10_1038-S44321-024-00129-8 | biostudies-other
ProteomicsThe interactional proteins with TANGO6 in U251 cells
To investigate the interactional proteins with TANGO6, we conducted MS.
ORGANISM(S): Homo Sapiens 
2024-02-04 | PXD049158 |
ProteomicsAspergillus niger An76 LC-MS/MS analysis
Xylan constituted with β-1,4-D-xylose linked backbone and diverse substituted side-chains is the most abundant hemicellulose component of biomass, which can be completely and rapidly degraded into fermentable sugars by Aspergillus niger. This is of great value for obtaining renewable biofuels and bi...
ORGANISM(S): Aspergillus Niger 
2018-02-06 | PXD008879 |
UnknownTANGO6 regulates cell proliferation via COPI vesicle-mediated RPB2 nuclear entry.
Not available
S-EPMC10943085 | biostudies-literature
ProteomicsMetrologically traceable quantification of three apolipoprotein E isoforms in cerebrospinal fluid
Apolipoprotein E (apoE) is a 317-amino-acid long glycoprotein with three common isoforms (apoE2, apoE3, and apoE4) encoded by three apoE alleles (ε2, ε3, and ε4). These polymorphic forms arise from single amino acid substitutions with Cys and Arg interchanged at positions 112 and 158 (mature protein...
ORGANISM(S): Homo Sapiens 
PXD038803 | panorama
TranscriptomicsFurin deficiency efect on T cells
Analysis of T-cells lacking the proprotein convertase furin. Proprotein convertases promote the proteolytic maturation of proproteins. Furin is induced in activated T-cells. Results provide insight into the function of furin in T-cells. CD4+CD62L+CD44- naive, CD4+CD62L-CD44+ memory and CD4+CD25+FoxP...
ORGANISM(S): Mus musculus 
2015-08-05 | E-GEOD-67884 | biostudies-arrayexpress
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