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TranscriptomicsIdentification of differentially expressed genes in Sfmbt1-knockdown C2C12 myoblasts
Gene expression profiling was performed to identify Sfmbt1-dependent regulation in myogenic programs. To establish the magnitude of the Sfmbt1 effect on muscle cells, we have compared gene expression profiles of C2C12 cells transduced with lentiviruses expressing scramble shRNA control or shSfmbt1. ...
ORGANISM(S): Mus musculus 
2013-01-28 | E-GEOD-24346 | biostudies-arrayexpress
TranscriptomicsIdentification of CRTC1-MAML2 fusion oncogene-regulated transcriptional program in H3118 cells
Mucoepidermoid carcinomas (MEC) is the most common salivary gland malignancy. To date, advanced and nonresectable MEC have poor prognosis and no effective treatment. The CRTC1-MAML2 fusion oncogene, which is associated with more than 50% of MEC, consists of the N-terminal CREB-binding domain of the...
ORGANISM(S): Homo sapiens 
2014-04-21 | E-GEOD-46580 | biostudies-arrayexpress
ProteomicsNuclear polysaccharides maintain H3K9me3-heterochromatin and genomic stability
Polysaccharides are traditionally confined to the cell surface and extracellular space, whereas their nuclear roles remain unclear. Here, we show that N-glycans are present in the nucleus and modify inner nuclear membrane (INM) proteins across multiple cell types. Disruption of INM protein N-glycosy...
ORGANISM(S): Mus Musculus 
2025-12-30 | PXD072505 |
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