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The role of progesterone receptor (PR) in breast cancer remains controversial with conflicting reports from both clinical and laboratory studies. To address these discrepancies, we conducted an integrated omics analysis using MCF-7 cells with elevated PR expression (MCF-7PR) through transfection. Tr...
ORGANISM(S): Homo sapiens (Human) 
2026-01-05 | PXD061206 | Pride
While thousands of long non-coding RNAs (lncRNAs) are expressed in higher eukaryotes, the potential regulatory roles of lncRNAs in regulated gene transcription programs remain rather poorly understood. Here, we report that two lncRNAs highly overexpressed in aggressive prostate cancer, PRNCR1 and PC...
ORGANISM(S): Homo sapiens 
To identify the potential receptor mediating the effect of Musclin on thermogenic adipocytes, we conducted a proximity-dependent biotin identification (BioID) assay to obtain the interactome of Musclin on the plasma membrane of beige adipocytes.
ORGANISM(S): Mus musculus (Mouse) 
2023-06-13 | PXD041019 | Pride
Mesenchymal stromal cell-derived extracellular vesicles (MSC-EVs) are recognized as a promising strategy for cell-free therapy, however, their therapeutic role in pulmonary fibrosis remains unrevealed. Here, we report the safety and efficacy of MSC-EVs from human umbilical cord (hUCMSC-EVs) evaluate...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD063385 | Pride
In plants, MicroRNAs (miRNAs) are a new class of endogenous small RNAs that play essential regulatory roles in plant growth, development and stress response. Extensive studies of miRNAs have been performed in model plants such as rice, Arabidopsis thaliana and other plants. However, the number of mi...
ORGANISM(S): Zea mays 
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