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MetabolomicsHistone serotonylation promotes pancreatic cancer development via lipid metabolism remodeling

Neurotransmitter serotonin (5-hydroxytryptamine [5-HT]) has emerged to play parallel roles in both neurobiology and oncology. Apart from receptor-mediated signaling transduction pattern, serotonin can be covalently integrated into histone (the post-translational modification known as histone sero...

2025-06-13 | MTBLS12569 | MetaboLights
MetabolomicsAltered metabolome and microbiome features provide clues in understanding irritable bowel syndrome and depression comorbidity

Irritable bowel syndrome (IBS) is one of the functional gastrointestinal disorders characterized by chronic and/or recurrent symptoms of abdominal pain and irregular defecation. Changed gut microbiota has been proposed to mediate IBS; however, contradictory results exist, and IBS-specific microbi...

2021-12-01 | MTBLS2774 | MetaboLights
TranscriptomicsAuxin-independent NAC pathway regulates cell wall metabolism in response to explant-specific wounding during regeneration in Arabidopsis II
In this study, through a genome-wide transcriptome analysis of wounding in the leaf explant, we identified NAC1 (petunia NAM and Arabidopsis ATAF1, ATAF2, and CUC2) family transcription factor gene that acts in response to wounding and functions in regulation of cell wall metabolism. RNA-Seq analys...
ORGANISM(S): Arabidopsis thaliana 
2015-12-31 | E-GEOD-74585 | biostudies-arrayexpress
TranscriptomicsAuxin-independent NAC pathway regulates cell wall metabolism in response to explant-specific wounding during regeneration in Arabidopsis I
In this study, through a genome-wide transcriptome analysis of wounding in the leaf explant, we identified NAC1 (petunia NAM and Arabidopsis ATAF1, ATAF2, and CUC2) family transcription factor gene that acts in response to wounding and functions in regulation of cell wall metabolism. RNA-Seq analys...
ORGANISM(S): Arabidopsis thaliana 
2015-12-31 | E-GEOD-74584 | biostudies-arrayexpress
UnknownAutophagy induction promoted by m6A reader YTHDF3 through translation upregulation of FOXO3 mRNA.
Not available
S-EPMC9532426 | biostudies-literature
ProteomicsLabel-free quantitative proteomics for screening dynamic autophagy-related proteins during nutrient deprivation in MEFs
A Label-free quantitative proteomic profiling was performed on MEFs with or without nutrient starvation.
ORGANISM(S): Mus Musculus 
2022-10-15 | PXD025450 |
ProteomicsDIA proteomics analysis of mice in models of myocardial infarction and heart failure with preserved ejection fraction (HFpEF).
The dataset includes two parts: a) Proteomics of mouse heart tissue 14 days after myocardial infarction and long-term exercised mice post-myocardial infarction for 14 days; b) Cardiac proteomics of a model of heart failure with preserved ejection fraction (HFpEF) induced by L-NAME and high-fat diet-...
ORGANISM(S): Mus Musculus 
2024-04-05 | PXD051242 |
ProteomicsLactylation modification omics analysis of six mouse heart samples was carried out via label-free 4D LC-MS/MS
Post-translational modification (PTM) refers to the chemical modification of proteins following translation, which can regulate protein activity, localization, folding, and interactions with other biomacromolecules (including proteins, nucleic acids, and lipids). Increasing evidence suggests that ma...
ORGANISM(S): Mus Musculus 
2026-03-30 | PXD076346 |
UnknownMortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-income, middle-income, and high-income countries: a multicentre, international, prospective cohort study.
Not available
S-EPMC8314066 | biostudies-literature
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