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TranscriptomicsTranscriptome Analysis of LincRNA TUNA Knockdown in Mouse Embryonic Stem Cells
Globel gene expression was analyzed by RNA-seq to study the role of lincRNA TUNA in pluripotent mouse embryonic stem cells. mRNA profiles of CCE mES cells with shRNA-mediated depletion of lincRNA TUNA on days 2, 4, and 6, compared to a control shRNA.
ORGANISM(S): Mus musculus 
2014-02-03 | E-GEOD-46730 | biostudies-arrayexpress
TranscriptomicsLarge intergenic non-coding RNAs as novel modulators of reprogramming: human embryonic stem cells, CD34+ cells, and CD34+ derived induced pluripotent stem cells (LincRNA expression)
LincRNA expression profiles of human embryonic stem cells, CD34+ cells, and CD34+ derived induced pluripotent stem cells Total RNA was extracted from human ESCs, CD34+ cells, and CD34+ derived iPSC lines, then hybridized to Nimblegen tiling array GPL8792; Human lincRNA 391k Tiling Array V2
ORGANISM(S): Homo sapiens 
2010-11-10 | E-GEOD-23970 | biostudies-arrayexpress
TranscriptomicsLarge intergenic non-coding RNAs as novel modulators of reprogramming: siRNA (gene expression)
lincRNA-ST8SIA3 was depleted using siRNAs and associated gene expression changes were profiled on Affymentrix arrays siRNAs targeting lincRNA-ST8SIA3 were transfected into human induced pluripotent stem cells; non-targeting siRNAs were used as controls GPL570 ;Affymetrix Human Genome U133 Plus 2.0 ...
ORGANISM(S): Homo sapiens 
2010-11-10 | E-GEOD-23973 | biostudies-arrayexpress
ProteomicsDiscovery of lincRNA-encoded Peptides: An Integrated Transcriptomics, Proteomics and Bioinformatics Approach
Long noncoding RNA (lncRNA) refers to the family of RNA transcripts with more than 200 nucleotides in length, but cannot encode proteins. lincRNA (long intergenic noncoding RNA) is a subset of lncRNA that do not overlap with known genes. Increasing evidences have shown that some of these transcripts...
ORGANISM(S): Mus musculus (Mouse) 
2020-05-12 | PXD013892 | Pride
Noncoding Micropeptide Orf prediction Sorf Lncrna Lincrna peptide Lincrna 
TranscriptomicsA long noncoding RNA lincRNA-EPS acts as a transcriptional brake to restrain inflammation
RNA-seq was performed in biological replicates (2 mice per group) of wild-type and lincRNA-EPS-/- BMDMs at 0, 2, and 6 hours after LPS treatment (100 ng/ml). RNA-seq libraries were prepared as described (Heyer et al., 2015). Briefly, ribosomal RNA (rRNA) was depleted using the Ribozero rRNA removal ...
ORGANISM(S): Mus musculus 
2016-07-29 | E-MTAB-4088 | biostudies-arrayexpress
GenomicsDeconstructing lincRNA regulation during ESC to NPC differentiation
Deconstructing lincRNA regulation during ESC to NPC differentiation
PRJNA420368 | ENA
TranscriptomicslincRNA Expression
There is growing recognition that mammalian cells produce many thousands of large intergenic transcripts. However, the functional significance of these transcripts has been particularly controversial. While there are some well-characterized examples, the vast majority (>95%) show little evidence of ...
ORGANISM(S): Mus musculus 
2009-01-01 | E-GEOD-13765 | biostudies-arrayexpress
UnknownLincRNA-p21 suppresses target mRNA translation.
Not available
S-EPMC3509343 | biostudies-literature
TranscriptomicsTissue-specific RNA-seq in human evoked inflammation identifies novel blood and adipose lincRNA signatures of cardio-metabolic diseases
Inappropriate or sustained activation of innate immunity is a pathologic feature of several common cardio-metabolic disorders. Little is known, however, about transcriptomic modulation during inflammatory stress in disease-relevant human tissues. We applied deep RNA sequencing (RNA-seq) during low-d...
ORGANISM(S): Homo sapiens 
2014-01-02 | E-GEOD-50792 | biostudies-arrayexpress
GenomicsLincRNA-EPS regulates iron metabolism and osteoclastogenesis under inflammatory micro-environment
LincRNA-EPS regulates iron metabolism and osteoclastogenesis under inflammatory micro-environment
PRJNA1305314 | ENA
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