Lineage factors

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Unknown (5127)
Genomics (3682)
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Other (151)
Proteomics (121)
Methylation profiling (73)
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Models (8)
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Organisms

Mus musculus (2038)
Homo sapiens (1241)
Rattus norvegicus (43)
Drosophila melanogaster (40)
Danio rerio (33)
Arabidopsis thaliana (22)
Schmidtea mediterranea (9)
Gallus gallus (9)
Xenopus laevis (8)
Caenorhabditis elegans (8)
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Candida albicans (7)
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Daphnia pulex (5)
Staphylococcus aureus (4)
Plasmodium falciparum (4)
Ciona intestinalis (3)
Chlamydomonas reinhardtii (3)
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Zymoseptoria tritici (1)
Fusarium oxysporum (1)
Lagenaria siceraria (1)
Cicer arietinum (1)
Puccinia graminis f. sp. tritici (1)
Moraxella catarrhalis RH4 (1)
Pongo pygmaeus (1)
Populus balsamifera (1)
Cryptococcus bacillisporus (1)
Pimephales promelas (1)
Rana temporaria (1)

Organisms

Mus musculus (1336)
Homo sapiens (848)
Rattus norvegicus (28)
Drosophila melanogaster (27)
Danio rerio (18)
Arabidopsis thaliana (10)
Schmidtea mediterranea (6)
Xenopus tropicalis (4)
Caenorhabditis elegans (4)
Staphylococcus aureus (4)
Bos taurus (4)
Triticum urartu (3)
Trypanosoma brucei brucei (2)
Elephas maximus (2)
Pinus densiflora (2)
Silene acaulis (2)
Piper sarmentosum (2)
Xenopus laevis (2)
Strongylocentrotus purpuratus (2)
Phyllostachys edulis (2)
Hydra vulgaris (2)
Macaca mulatta (2)
Candida albicans (2)
Plasmodium falciparum (2)
Toxoplasma gondii (2)
Gallus gallus (2)
unidentified (2)
Fusarium oxysporum f. sp. pisi HDV247 (1)
Fusarium oxysporum f. sp. lycopersici MN25 (1)
Mus musculus musculus x Mus musculus castaneus (1)

Repository

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geo (2322)
biostudies-arrayexpress (1147)
pride (96)
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Tissue

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Disease

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Technology Type

Mass Spectrometry (96)
Shotgun proteomics (47)
Affinity purification coupled with mass spectrometry proteomics (30)
Bottom-up proteomics (21)
Data-dependent acquisition (13)
Mass spectrometry assay (8)
Mass spectrometry (8)
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SWATH MS (5)
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SRM/MRM (3)
NMR spectroscopy (2)
DiaPASEF (2)
Humanomniexpress-24-v1-1-a, Illumina HiSeq 2000, HiSeq X Ten, Illumina HiSeq 2500, Illumina HiSeq 4000, ILLUMINA (1)
Illumina HumanOmniExpress-FFPE-12 v1.0 BeadChip (1)
ILLUMINA, Illumina HiSeq 2500 (1)
Illumina HiSeq 4000, Illumina HiSeq 2500, ILLUMINA (1)
Illumina HiSeq 2500, Illumina MiSeq, NextSeq 500, Illumina HiSeq 2000 (1)
Affinity proteomics (1)

Instrument Platform

Illumina NovaSeq 6000 (26)
Illumina HiSeq 2500 (16)
Illumina HiSeq 4000 (10)
Illumina HiSeq 2000 (9)
NextSeq 500 (8)
Illumina Genome Analyzer II (3)
Illumina HiSeq 3000 (3)
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STAR v2.5.3a, rpkmforgenes, RSeQC 2.6.1 (1)
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Oligo(dT) primer and SuperScript II reverse transcriptase (ThermoFisher Scientific), TapeStation 4200 or 2100 Bioanalyzer with a DNA High Sensitivity chip (Agilent Biotechnologies) (1)
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STAR (1)
Single Cell/Low Input RNA Library Prep Kit for Illumina (#E6420S, New England Biolabs) (1)
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FACS (1)
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Agilent Surescan High Resolution DNA Microarray Scanner (1)
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Illumina Genome Analyzer IIx (1)

Publication Date

2025 (300)
2026 (266)
2024 (260)
2013 (253)
2014 (252)
2015 (246)
2023 (238)
2022 (224)
2020 (195)
2021 (192)
2012 (189)
2019 (166)
2016 (156)
2011 (140)
2010 (126)
2017 (123)
2018 (115)
2008 (72)
2009 (58)
2007 (39)
2005 (5)
2006 (2)

UNIPROT ID/AC

Q15406 (2)
Q99626 (2)
Q92908 (2)
Q6ZRP7 (2)
Q8N7R0 (2)
Q01860 (2)
P04637 (2)
Q99JB6 (1)
P51450 (1)
P04202 (1)
P42227 (1)
P08505 (1)
P97378 (1)
P01580 (1)
Q9JKD8 (1)

ENSEMBL ID

ENSG00000148200 (2)
ENSG00000165556 (2)
ENSG00000141448 (2)
ENSG00000165661 (2)
ENSG00000176654 (2)
ENSG00000204531 (2)

CHEBI ID

CHEBI:16856 (4)
CHEBI:17191 (4)
CHEBI:15354 (4)
CHEBI:17295 (4)
CHEBI:17634 (3)
CHEBI:15824 (3)
CHEBI:15741 (3)
CHEBI:17154 (3)
CHEBI:17115 (3)
CHEBI:16335 (3)
CHEBI:7916 (3)
CHEBI:16467 (3)
CHEBI:15891 (3)
CHEBI:16411 (3)
CHEBI:15971 (3)
CHEBI:422 (3)
CHEBI:15318 (3)
CHEBI:17053 (3)
CHEBI:16015 (3)
CHEBI:32816 (3)
CHEBI:16027 (3)
CHEBI:16414 (3)
CHEBI:15603 (3)
CHEBI:17895 (3)
CHEBI:30769 (3)
CHEBI:34595 (2)
CHEBI:6804 (2)
CHEBI:16523 (2)
CHEBI:28315 (2)
CHEBI:33699 (1)

Metabolite Name

Choline (6)
Adenosine (6)
L-Isoleucine (6)
L-Valine (5)
L-Tyrosine (5)
L-Phenylalanine (5)
Inosine (5)
Niacinamide (4)
L-Histidine (4)
L-Glutamic acid (4)
Acetylcholine (4)
Methionine (4)
Taurine (4)
4-Hydroxybenzaldehyde (4)
Citric acid (4)
Oleamide (4)
Tyramine (4)
Urocanic acid (4)
Spermidine (4)
2-Hydroxycinnamic acid (4)
L-Tryptophan (4)
Hypoxanthine (4)
N-Methylhydantoin (3)
S-Lactoylglutathione (3)
D-Serine (3)
Pyruvic acid (3)
D-Glucose (3)
Glycine (3)
Cyclohexylamine (3)
Phenylacetic acid (3)

First Public Date

2025 (299)
2024 (288)
2026 (274)
2023 (269)
2014 (254)
2022 (237)
2020 (191)
2021 (182)
2019 (165)
2017 (124)
2018 (120)
2015 (100)
2013 (93)
2016 (73)
2012 (7)
2011 (1)
2010 (1)

Modelling Approach

Ordinary differential equation model (5)

Lab affiliation

Technical University of Munich, School of Medicine, Institute of Virology, 81675 Munich, Germany (3)
1. Faculty of Biology, Technion - Israel Institute of Technology, Haifa 320003, Israel 2. Computer Science Department, Technion - Israel Institute of Technology, Haifa 320003, Israel (2)
Department of Biochemistry UT Southwestern Medical Center (2)
Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, USA (2)
Department of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences (RIMLS), Oncode Institute, Radboud University Nijmegen, 6525 GA Nijmegen, The Netherlands Division of Molecular Genetics, The Netherlands Cancer Institute, 1066CX, Amsterdam, The Netherlands (2)
Department of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences, Oncode Institute, Radboud University Nijmegen, 6525 GA Nijmegen, The Netherlands (2)
Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Denmark (2)
University of Edinburgh (2)
1. Faculty of Biology, Technion - Israel Institute of Technology, Haifa 320003, Israel. 2. Computer Science Department, Technion - Israel Institute of Technology, Haifa 320003, Israel. (1)
Assistant Member, Immunology Department St. Jude Children's Research Hospital Memphis, TN USA (1)
Babraham Institute (1)
Baxter Laboratory for Stem Cell Biology Department of Microbiology & Immunology Stanford University School of Medicine 269 Campus Drive CCSR 3205b Stanford, CA 94305-5175, USA (1)
CNIO (1)
Cambridge Institute for Medical Research, University of Cambridge, Hills Road, Cambridge, CB2 0XY, UK (1)
Carnegie Mass Spectometry facility Carnegie Science at Stanford (1)
Carnegie Mass Spectrometry Facility at Stanford (1)
Center for Organismal Studies (COS) Heidelberg, University of Heidelberg (Germany) (1)
Centre for Drug Safety Science, Dept Pharmacology and Therapeutics, Institute for Systems, Molecular and Integrative Biology, University of Liverpool (1)
Centre for Drug Safety Science, Dept Pharmacology and Therapeutics, Institute of Systems, Molecular and Integrative Biology, University of Liverpool (1)
Chair of Biochemistry II, Theodor Boveri-Institute, Biocenter, University of Würzburg, Würzburg, Germany (1)
Chair of Proteomics and Bioanalytics, TU Munich (1)
Children's Medical Research Insitute, The University of Sydney (1)
China Medical University (1)
Chromatin Biology Laboratory, Josep Carreras Leukaemia Research Institute (IJC), Ctra de Can Ruti, Camí de les Escoles s/n, 08916, Badalona, Barcelona, Spain (1)
Cleveland Clinic (1)
Dame Roma Mitchell Cancer Research Laboratories, Adelaide Medical School, University of Adelaide, Adelaide, Australia (1)
Departamento de Biología Celular, Biología Funcional y Antropología Física,Instituto de Biotecnología y Biomedicina (1)
Departement for Biomedical Research University of Bern Switzerland (1)
Department of Anatomy and Developmental Biology, Australian Regenerative Medicine Institute, Monash University, Australia (1)
Department of Biochemistry and Molecular Biology, Sidney Kimmel Medical College, Thomas Jefferson University, 233 S 10th Street, BLSB 826, Philadelphia, PA, 19104 (1)

IsPrivate

False (5)

Classification

bacteria (15)
fungi (11)
protozoa (6)
viruses (1)

Modification

6-dioxaoctanediamine derivatized cysteine (1)

Study type

Transcription profiling by array (599)
ChIP-seq (188)
RNA-seq of coding RNA (185)
RNA-seq of coding RNA from single cells (25)
Methylation profiling by array (22)
Methylation profiling by high throughput sequencing (17)
ChIP-chip by tiling array (16)
Comparative genomic hybridization by array (15)
Unknown experiment type (11)
Other (11)
RNA-seq of non coding RNA (11)
ChIP-chip by array (5)
Genotyping by array (5)
Differential (3)
Human - High-throughput sequencing (3)
MicroRNA profiling by array (3)
DNA-seq (3)
Cell line - Single-cell sequencing (2)
Animal - One-color microarray (2)
Animal - Single-cell sequencing (2)
Transcription profiling by tiling array (2)
RNAi profiling by array (2)
Transcription profiling by RT-PCR (2)
ATAC-seq (2)
RNA-seq of total RNA (2)
FAIRE-seq (1)
Baseline (1)
Human - Two-color microarray (1)
Human - Methylation microarray (1)
Human - Single-cell sequencing (1)

Release Date

2021 (443)
2022 (442)
2023 (436)
2015 (423)
2025 (415)
2014 (411)
2013 (392)
2018 (361)
2020 (360)
2016 (358)
2024 (354)
2017 (312)
2019 (296)
2012 (292)
2010 (228)
2011 (219)
2008 (142)
2009 (133)
2007 (71)
2026 (68)
2006 (34)
2005 (28)
2004 (15)
2002 (12)
2003 (10)
2001 (5)
1998 (5)
1999 (4)
2000 (1)
1997 (1)

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Released palmitic acid–mediated TLR4/NF-κB activation enhances the virulence of Bordetella pertussis MT28 lineage

Whooping cough resurged globally despite the widespread vaccination. A macrolide-resistant (MR) lineage carrying the high-virulence ptxP3 allele, ptxP3 MR-MT28 (MT28), has imposed a substantial burden on pertussis epidemics, while the underlying factors driving its prevalence remain unclear. Thus...

2025-12-21 | MTBLS13545 | MetaboLights

Palmitic acid-mediated TLR4/NF-κB activation drives the pathogenicity of hypervirulent Bordetella pertussis MT28 lineage

2025-06-21 | MTBLS12625 | MetaboLights

A gut-associated Prevotellaceae_NK3B31_group lineage modulates host metabolic pathways and enhances feed efficiency in ducks

Amidst the mismatch between domestic feed supply and demand in China, along with the competition for food between humans and animals, optimizing feed efficiency has become crucial for industry growth. Nevertheless, the biological processes driving variations in feed efficiency remain unexplored. ...

2026-03-10 | MTBLS14013 | MetaboLights

A gut-associated Prevotellaceae_NK3B31_group lineage modulates host metabolic pathways and enhances feed efficiency in ducks

2026-03-10 | MTBLS14017 | MetaboLights

A gut-associated Prevotellaceae_NK3B31_group lineage modulates host metabolic pathways and enhances feed efficiency in ducks

2026-03-10 | MTBLS14009 | MetaboLights

Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities

Genome-scale studies have revealed extensive co-localization of transcription factors in a given cell type as well as substantial differences in the binding patterns of specific transcription factors between cell types. Several mechanisms have been proposed to explain these observations, including t...

ORGANISM(S): Mus musculus

2010-05-27 | E-GEOD-21512 | biostudies-arrayexpress

Sequentially acting Sox transcription factors in neural lineage development [RNA-seq]

We report sequential binding but unique functions of different Sox transcription factors during distinct stages of neural differentiation Loss of function experiment for Sox2/Sox3 in neural progenitor cells and gene expression profile for Sox11 expressing (PSA NCAM sorted) early formed neurons.

ORGANISM(S): Mus musculus

2011-11-01 | E-GEOD-33060 | biostudies-arrayexpress

Divergent functions of hematopoietic transcription factors in lineage priming and differentiation during erythro-megakaryopoiesis

Combinatorial actions of relatively few transcription factors control hematopoietic differentiation. To investigate this process in erythro-megakaryopoiesis, we correlated the genome-wide chromatin occupancy signatures of four master hematopoietic transcription factors (GATA1, GATA2, TAL1, and FLI1)...

ORGANISM(S): Mus musculus

2014-11-14 | E-GEOD-51337 | biostudies-arrayexpress

Lung adenocarcinoma metastasis is suppressed by the alveolar lineage transcription factors GATA6 and HOPX.

Molecular programs that mediate normal cell differentiation are required for oncogenesis and tumor cell survival in certain types of cancers. How cell lineage restricted genes specifically influence metastatic progression is poorly defined. In lung cancers, we uncovered an alveolar cell-selective tr...

ORGANISM(S): Homo sapiens

2013-06-10 | E-GEOD-39121 | biostudies-arrayexpress

Mutant Huntingtin promotes neuronal death through cell autonomous microglial activation via myeloid lineage- determining factors

Huntington's Disease (HD) is a fatal neurodegenerative disorder caused by an extended polyglutamine repeat in the N-terminus of the huntingtin (Htt) protein. Reactive microglia and elevated cytokine levels are observed in the brains of HD patients, but the extent to which neuroinflammation results f...

ORGANISM(S): Mus musculus

2014-03-02 | E-GEOD-54443 | biostudies-arrayexpress

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11494 Results

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