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ProteomicsZFP462 safeguards neural lineage specification by targeting G9A/GLP-mediated heterochromatin to silence enhancers
ZNF462 haploinsufficiency is linked to Weiss-Kruszka Syndrome, a genetic disorder characterized by neurodevelopmental defects including Autism. Though conserved in vertebrates and essential for embryonic development the molecular functions of ZNF462 remain unclear. We identified its murine homolog Z...
ORGANISM(S): Mus musculus (Mouse) 
2023-05-10 | PXD037238 | Pride
Stem cells Lineage specification and heterochromatin Transcription factors Zfp462 
TranscriptomicsP. falciparum Heterochromatin Protein 1 Marks Genomic Loci Linked to Phenotypic Variation of Exported Virulence Factors
Epigenetic processes are the main conductors of phenotypic variation in eukaryotes. The malaria parasite Plasmodium falciparum employs antigenic variation of the major surface antigen PfEMP1, encoded by 60 var genes, to evade acquired immune responses. PfEMP1 also mediates sequestration of infected ...
ORGANISM(S): Plasmodium falciparum 
2010-05-06 | E-GEOD-17029 | biostudies-arrayexpress
GenomicsZFP462 safeguards neural lineage specification by targeting G9A/GLP mediated heterochromatin to silence enhancers
ZFP462 safeguards neural lineage specification by targeting G9A/GLP mediated heterochromatin to silence enhancers
PRJNA732185 | ENA
GenomicsLoss of H3K9me3 heterochromatin at protein coding genes enables developmental lineage specification (srHC-seq)
Loss of H3K9me3 heterochromatin at protein coding genes enables developmental lineage specification (srHC-seq)
PRJNA470542 | ENA
GenomicsZFP462 safeguards neural lineage specification by targeting G9A/GLP mediated heterochromatin to silence enhancers [QuantSeq]
ZFP462 safeguards neural lineage specification by targeting G9A/GLP mediated heterochromatin to silence enhancers [QuantSeq]
PRJNA735763 | ENA
GenomicsLoss of H3K9me3 heterochromatin at protein coding genes enables developmental lineage specification (RNA-Seq)
Loss of H3K9me3 heterochromatin at protein coding genes enables developmental lineage specification (RNA-Seq)
PRJNA470536 | ENA
GenomicsLoss of H3K9me3 heterochromatin at protein coding genes enables developmental lineage specification (ChIP-Seq)
Loss of H3K9me3 heterochromatin at protein coding genes enables developmental lineage specification (ChIP-Seq)
PRJNA470537 | ENA
UnknownH3K9me3-heterochromatin loss at protein-coding genes enables developmental lineage specification.
Not available
S-EPMC6664818 | biostudies-literature
UnknownZFP462 safeguards neural lineage specification by targeting G9A/GLP-mediated heterochromatin to silence enhancers.
Not available
S-EPMC10038669 | biostudies-literature
GenomicsZFP462 safeguards neural lineage specification by targeting G9A/GLP mediated heterochromatin to silence enhancers [RNA-seq]
ZFP462 safeguards neural lineage specification by targeting G9A/GLP mediated heterochromatin to silence enhancers [RNA-seq]
PRJNA735881 | ENA
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