Sort   by:  
 Page size 
The translation inhibitor Linezolid is an important antibiotic of last resort against multiresistant gram-positive pathogens including MRSA. Linezolid is reported to specifically inhibit extracellular virulence factors, but the molecular cause is unknown. To elucidate the physiological response of S...
ORGANISM(S): Staphylococcus aureus 
2016-03-18 | PXD001659 | Pride
Transcriptional profiling of Mycobacterium tuberculosis H37Rv strains comparing control DMSO treated strains with Linezolid treated strains. Goal was to determine the effects of Linezolid against Mycobacterium tuberculosis H37Rv strains. Two-condition experiment,control DMSO treated strains vs. Line...
ORGANISM(S): Mycobacterium tuberculosis 
The translation inhibitor Linezolid is an important antibiotic of last resort against multiresistant gram-positive pathogens including MRSA. Linezolid is reported to specifically inhibit extracellular virulence factors, but the molecular cause is unknown. To elucidate the physiological response of S...
ORGANISM(S): Staphylococcus aureus (strain USA300) 
2016-03-18 | PXD001622 | Pride
Exponentially growing S.aureus ATCC 25923 was treated with linezolid (LZD) at concentrations of 1/2× MIC, 1× MIC, and 5× MIC, or an equivalent amount of DMSO for 1 hour. The bacteria were pelleted by centrifugation and washed twice with saline. The samples were then re-suspended in bacteria lysis bu...
ORGANISM(S): Staphylococcus aureus 
2023-12-11 | PXD046938 | Pride
The precise mechanism and effects of antibiotics in host gene expression and immunomodulation in MRSA infection is unknown. Using a well characterized Methicillin Resistant Staphylococcus aureus (MRSA) isolate USA300 in a murine model of infection, we determined that linezolid and vancomycin induced...
ORGANISM(S): Mus musculus 
The translation inhibitor Linezolid is an important antibiotic of last resort against multiresistant gram-positive pathogens including MRSA. Linezolid is reported to specifically inhibit extracellular virulence factors, but the molecular cause is unknown. To elucidate the physiological response of S...
ORGANISM(S): Staphylococcus aureus 
The study aims to identify genes associated with Linezolid resistance. Linezolid resistant strains were compared to a Linezolid sensitive reference strain in the presence of linezolid and absence of linezolid (mock).
ORGANISM(S): Staphylococcus aureus 
2011-04-08 | GSE26358 | GEO
Transcriptional profiling of Mycobacterium tuberculosis H37Rv strains comparing control DMSO treated strains with Linezolid treated strains. Goal was to determine the effects of Linezolid against Mycobacterium tuberculosis H37Rv strains.
ORGANISM(S): Mycobacterium tuberculosis Mycobacterium tuberculosis H37Rv 
2011-10-11 | GSE32718 | GEO
Arg C and Linezolid on Th17 cells
Transcriptional Response of Mycobacterium tuberculosis H37Rv to linezolid
Sort   by:  
 Page size