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Transcriptomicsshld1 effect on 3T3 cell
NIH3T3 cells were cultured in medium containing 1 uM, 100 nM, 10 nM and 0 nM (serve as control) shld1 for 24 hours. Three independent cultures were obtained for each drug concentration. Total RNA from experimental samples were extracted using RNeasy Kit (Qiagen). Mouse RNA pooled from 11 cell line...
ORGANISM(S): Mus musculus 
2007-09-27 | E-GEOD-5916 | biostudies-arrayexpress
GenomicsImpacts of the Ubiquitous Factor Zelda on Bicoid-dependent DNA-binding and Transcription in Drosophila
In vivo crosslinking studies suggest that the Drosophila transcription factor Bicoid (Bcd) binds to several thousand sites during early embryogenesis, but it is not clear how many of these binding events are functionally important. In contrast, reporter gene studies have identified more than 60 Bcd-...
ORGANISM(S): Drosophila melanogaster 
2014-05-02 | E-GEOD-55256 | biostudies-arrayexpress
UnknownBoron-Insertion-Induced Lattice Engineering of Rh Nanocrystals Toward Enhanced Electrocatalytic Conversion of Nitric Oxide to Ammonia.
Not available
S-EPMC12496378 | biostudies-literature
TranscriptomicsProfiling circulating microRNA expression in a mouse model of nerve allotransplantation (part 2)
Background. The lack of noninvasive biomarkers of rejection remains a challenge in the accurate monitoring of deeply buried nerve allografts and precludes optimization of therapeutic intervention. This study aimed to establish the expression profile of circulating microRNAs (miRNAs) during nerve all...
ORGANISM(S): Mus musculus 
2014-07-01 | E-GEOD-48971 | biostudies-arrayexpress
TranscriptomicsProfiling circulating microRNA expression in a mouse model of nerve allotransplantation (part 1)
Background. The lack of noninvasive biomarkers of rejection remains a challenge in the accurate monitoring of deeply buried nerve allografts and precludes optimization of therapeutic intervention. This study aimed to establish the expression profile of circulating microRNAs (miRNAs) during nerve all...
ORGANISM(S): Mus musculus 
2014-07-01 | E-GEOD-48969 | biostudies-arrayexpress
TranscriptomicsDisrupted processing of long pre-mRNAs and widespread RNA missplicing are components of neuronal vulnerability from loss of nuclear TDP-43 (CLIP)
Cross-linking and immunoprecipitation coupled with high-throughput sequencing was used to identify binding sites within 6,304 genes as the brain RNA targets for TDP-43, an RNA binding protein which when mutated causes Amyotrophic Lateral Sclerosis (ALS). Use of massively parallel sequencing and spli...
ORGANISM(S): Mus musculus 
2011-03-03 | E-GEOD-27201 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of wild type and crc mutant Pseudomonas putida growing exponentially in LB medium
Effect of inactivating the crc gene (PP_5292) on the transcriptome of cells growing exponentially in LB medium
ORGANISM(S): Pseudomonas putida 
2009-11-03 | E-MEXP-1886 | biostudies-arrayexpress
GenomicsGenome wide H3K9ac and SAGA occupancy at OX growth phase and RC quiescent phase of yeast metabolic cycle
We found acetyl-CoA levels increase when cells are committed to growth. We also found 3 components of the SAGA complex, Spt7p, Sgf73p and Ada3p as well as histones are dynamically acetylated in tune with the acetyl-CoA levels. ChIP-seq study reveals SAGA and H3K9ac predominantly occupy growth genes ...
ORGANISM(S): Saccharomyces cerevisiae 
2011-05-19 | E-GEOD-28734 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of Pseudomonas putida KT2442 and KT42C1
Effect of inactivating the phaC1 gene (PP_5003) on the transcriptome of cells growing exponentially in PHA production medium
ORGANISM(S): Pseudomonas putida 
2011-12-01 | E-MEXP-3183 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Pseudomonas putida KT2442 and KT42F
Effect of inactivating the phaF gene (PP_5007) on the transcriptome of cells growing exponentially in PHA production medium
ORGANISM(S): Pseudomonas putida 
2010-12-01 | E-MEXP-2970 | biostudies-arrayexpress
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