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ProteomicsThiol-cleavable Biotin for Chemical and Enzymatic Biotinylation and its Application to Mitochondrial TurboID Proteomics
Protein biotinylation via chemical or enzymatic reactions is often coupled with streptavidin-based enrichment and on-beads digestion in numerous biological applications. However, the popular on-beads digestion method faces major challenges of streptavidin contamination, the lost information of bioti...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-04-21 | MSV000087256 | MassIVE
ProteomicsProtein Contaminants Matter: Building Universal Protein Contaminant Libraries for DDA and DIA Proteomics
Mass spectrometry-based proteomics is challenged by the presence of contaminant background signals. In particular, protein contaminants from reagents and sample handling are often abundant and almost impossible to avoid, reducing the sensitivity, specificity and reproducibility of protein identifica...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2022-01-21 | MSV000088714 | MassIVE
MetabolomicsGNPS - Integrated proteomic and metabolomic analyses of the mitochondrial neurodegenerative disease MELAS
MELAS (mitochondrial encephalomyopathy, lactic acidosis, stroke-like episodes) is a progressive neurodegenerative disease caused by pathogenic mitochondrial DNA variants. The pathogenic mechanism of MELAS remains enigmatic due to the exceptional clinical heterogeneity and the obscure genotype-phenot...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-10-16 | MSV000088237 | GNPS
ProteomicsIntegrated proteomic and metabolomic analyses of the mitochondrial neurodegenerative disease MELAS
MELAS (mitochondrial encephalomyopathy, lactic acidosis, stroke-like episodes) is a progressive neurodegenerative disease caused by pathogenic mitochondrial DNA variants. The pathogenic mechanism of MELAS remains enigmatic due to the exceptional clinical heterogeneity and the obscure genotype-phenot...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-10-16 | MSV000088237 | MassIVE
UnknownBioinspired Ion Host with Buried and Consecutive Binding Sites for Controlled Ion Dislocation.
Not available
S-EPMC11600180 | biostudies-literature
Proteomicscentipedegrass tiller bud and internode proteome
This study investigate the differentially expressed proteins in tiller bud and internode between a high tillering mutant and wild type.
ORGANISM(S): Eremochloa ophiuroides 
2024-06-16 | PXD047559 | Pride
Centipedegrass Tiller bud Proteome 
MetabolomicsPKM2 methylation by CARM1 activates aerobic glycolysis to promote tumorigenesis
Metabolic reprogramming is a hallmark of cancer. Herein we discover that the key glycolytic enzyme pyruvate kinase M2 isoform (PKM2), but not the related isoform PKM1, is methylated by co-activator-associated arginine methyltransferase 1 (CARM1). PKM2 methylation reversibly shifts the balance of met...
2021-07-30 | MTBLS533 | MetaboLights
MetabolomicsA longitudinal ¹H NMR-based urinary metabolomics dataset in a birth cohort for childhood atopic diseases

This dataset presents longitudinal urinary metabolomic profiles from 198 children at 1 month, 6 months, 1 year, 3 years and 5 years. It includes demographic data, feeding practices, parental atopy, household income and atopic disease status over time. Total and allergen-specific IgE (mite, egg, c...

2025-07-28 | MTBLS12785 | MetaboLights
TranscriptomicsRNA-seq of HIV-1 infected long-term non-progressors(LTNPs) and typical progressors(TPs)
HIV-infected long-term non-progressors (LTNPs) are a special group of people who can naturally control HIV and maintain good host immunity. Their mechanism is related to viruses, host genetic characteristics, immune response and other factors, but the relationship between the activation level of in...
ORGANISM(S): Homo sapiens 
2021-02-10 | E-MTAB-9997 | biostudies-arrayexpress
MetabolomicsThe trans-omics landscape of COVID-19
The outbreak of coronavirus disease 2019 (COVID-19) is a global health emergency. Various omics results have been reported for COVID-19, but the molecular hallmarks of COVID-19, especially in those patients without comorbidities, have not been fully investigated. Here we collect blood samples from 2...
2021-10-06 | MTBLS2542 | MetaboLights
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