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MetabolomicsAngiopoietin-like 4 governs diurnal lipoprotein lipase activity in brown adipose tissue.

OBJECTIVE: Brown adipose tissue (BAT) burns fatty acids (FAs) to produce heat, and shows diurnal oscillation in glucose and triglyceride (TG)-derived FA-uptake, peaking around wakening. Here we aimed to gain insight in the diurnal regulation of metabolic BAT activity.

2023-11-15 | MTBLS4082 | MetaboLights
MetabolomicsLipidomics of hormone-sensitive lipase variants
Not available
ORGANISM(S): Homo sapiens 
ST000662 | MetabolomicsWorkbench
TranscriptomicsTranscription profiling of mouse soleus muscle from hormone sensitive lipase-null animals
Expression analysis in order to elucidatethe role of hormone-sensitive lipase in soleus muscle.
ORGANISM(S): Mus musculus 
2008-06-11 | E-GEOD-1772 | biostudies-arrayexpress
TranscriptomicsGene profile of Myeloid derived Suppressive Cells from the Bone Marrow of Lysosomal Acid Lipase Knock-out Mice
Expression profile of MDSC isolated from Bone marrow of lysosomal acid Lipase mice compared to the WT counterpart four samples
ORGANISM(S): Mus musculus 
2012-03-06 | E-GEOD-29401 | biostudies-arrayexpress
TranscriptomicsM-OM-^CB-dependent yabJ-spoVG operon involved in regulation of extracellular nuclease, lipase and protease expression in Staphylococcus aureus
The alternative sigma factor M-OM-^CB of Staphylococcus aureus is involved in the coordination of the general stress response, expression of virulence determinants and modulation of antibiotic resistance levels. It controls a large regulon, either directly by recognizing conserved M-OM-^CB promoter ...
ORGANISM(S): Staphylococcus aureus 
2011-11-23 | E-GEOD-30115 | biostudies-arrayexpress
MetabolomicsAn overexpression of lipoprotein lipase leads to an alteration in the skeletal muscle metabolome in transgenic rabbits
Not available
ORGANISM(S): Oryctolagus cuniculus 
ST001684 | MetabolomicsWorkbench
TranscriptomicsWhole genome expression profiling of rice leaves treated with Xanthomonas oryzae pv. oryzae secreted cell wall degrading lipase/esteraseA (LipA) at early time points, 30 min. and 120 min.
Treatment of rice tissues with purified preparations of a Xanthomonas oryzae pv. oryzae (Xoo) secreted plant cell wall degrading enzyme, Lipase/Esterase (LipA), elicits cell wall damage induced innate immune responses. LipA activity is required for induction of defense responses. In order to charact...
ORGANISM(S): Oryza sativa 
2015-06-30 | E-GEOD-53940 | biostudies-arrayexpress
TranscriptomicsThe ER-Associated Degradation Adapter Protein Sel1L Regulates Triglyceride Metabolism via Lipoprotein Lipase
Sel1L is an adaptor protein for the E3 ligase Hrd1 in the endoplasmic reticulum-associated degradation (ERAD), but its physiological role in a cell-type-specific manner remains unclear. Here we show that mice with adipocyte-specific Sel1L deficiency are resistant to diet-induced obesity and exhibit ...
ORGANISM(S): Mus musculus 
2015-05-18 | E-GEOD-56918 | biostudies-arrayexpress
ProteomicsOptimization of conditions and treatment order for lipase application in plasma
To complement this approach, the second objective of this study is to address the underrepresentation of membrane proteins in plasma proteomics by investigating the use of lipase as a tool to enhance their extraction.
ORGANISM(S): Homo sapiens (Human) 
2026-09-14 | PXD064099 | Pride
Human Dia Plasma Lc-ms/ms 
TranscriptomicsPrdm5 suppresses ApcMin-driven intestinal adenomas and regulates monoacylglycerol lipase expression
PRDM proteins are tissue specific transcription factors often deregulated in diseases, particularly in cancer where different members have been found to act as oncogenes or tumor suppressors. PRDM5 is a poorly characterized member of the PRDM family for which several studies have reported a high fre...
ORGANISM(S): Mus musculus 
2013-05-11 | E-GEOD-46821 | biostudies-arrayexpress
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