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MetabolomicsUPLC-Q-TOF/MS-Based Plasma and Urine Metabolomics Contribute to the Diagnosis of Sepsis
In this study, we aimed to identify potential metabolic biomarkers that can improve the diagnostic accuracy of sepsis. Sixty-six patients including 30 septic and 36 nonsepsis patients from an intensive care unit were recruited. The global plasma and urine metabolomic profiles were determined by ultr...
2023-04-18 | MTBLS3505 | MetaboLights
MetabolomicsDistinct metabolic profiling is correlated with bisexual flowers formation resulting from exogenous ethephon induction in melon (Cucumis melo L.)

Melon (Cucumis melo L.) is an agronomically important vegetable. Most cultivars of melon are andromonoecious and bisexual flowers only emerged from the leaf axil of lateral branches. However, the regulatory mechanism contributing to the occurrence of bisexual flowers were still obscure. ...

2022-03-10 | MTBLS2993 | MetaboLights
ProteomicsIntegrative Multianalytical Model Based on Novel Plasma Protein Biomarkers for Distinguishing Lung Adenocarcinoma and Benign Pulmonary Nodules
Given the pressing clinical problem of making decision in diagnosis for subjects with pulmonary nodules, we aimed to discover novel plasma protein biomarkers for lung adenocarcinoma (LUAD) and benign pulmonary nodules (BPN), then develop an integrative multianalytical model to guide the clinical man...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD046731 | Pride
Differential diagnosis Integrative multianalytical model Lung adenocarcinoma Plasma proteomics Benign pulmonary nodules 
MetabolomicsUltraperformance Liquid Chromatography Coupled with Quadrupole Time-of-Flight Mass Spectrometry-Based Metabolomics and Lipidomics Identify Biomarkers for Efficacy Evaluation of Mesalazine in a Dextran Sulfate Sodium-Induced Ulcerative Colitis Mouse Model
This study aims to identify biomarkers for evaluating the therapeutic efficacy of mesalazine on ulcerative colitis by metabolomics and lipidomics. A dextran sulfate sodium-induced mouse model was used. The disease status was assessed by a disease activity index, the TNF-α level of colon was measured...
2022-10-24 | MTBLS2111 | MetaboLights
UnknownEfficacy of ultra-short course chemotherapy for new smear positive drug susceptible pulmonary tuberculosis: study protocol of a multicenter randomized controlled clinical trial.
Not available
S-EPMC5474865 | biostudies-literature
UnknownATP1A3 mosaicism in families with alternating hemiplegia of childhood.
Not available
S-EPMC6850116 | biostudies-literature
UnknownInactivation of HMGCL promotes proliferation and metastasis of nasopharyngeal carcinoma by suppressing oxidative stress.
Not available
S-EPMC5607293 | biostudies-literature
ProteomicsGenome-wide identification and proteomic analysis of the wheat ABCG family reveals a pivotal role of TaABCG7B-8 in fertility conversion of a photoperiod-temperature sensitive genic male sterility wheat
Photoperiod- and temperature-sensitive genic male sterility (PTGMS) plays a central role in two-line hybrid wheat breeding, yet its underlying molecular mechanisms remain incompletely understood. In this study, we performed a genome-wide identification of the ATP-binding cassette subfamily G (ABCG) ...
ORGANISM(S): Triticum Aestivum 
2026-01-04 | PXD072615 |
UnknownAcute kidney injury in hospitalized patients with nonmalignant pleural effusions: a retrospective cohort study.
Not available
S-EPMC10983765 | biostudies-literature
TranscriptomicsRNA-seq analysis of crypt samples isolated from the small intestine of Bach2 KO and control mice
Epithelial regeneration is critical for barrier maintenance and organ function after intestinal injury. Here, we found that Bach2 deficiency promotes the intestinal epithelial cell proliferation during homeostasis and facilitates the crypt regeneration after irradiation, resulting in a reduction of ...
ORGANISM(S): Mus musculus 
2021-01-12 | E-MTAB-9865 | biostudies-arrayexpress
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