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ProteomicsOxadiazolone derivatives against M. tuberculosis
Oxadiazolone (OX) derivatives have been investigated for their antimycobacterial activity against three pathogenic slow-growing mycobacteria: Mycobacterium marinum, Mycobacterium bovis BCG and the avirulent Mycobacterium tuberculosis (M. tb) mc26230. The encouraging MIC values obtained prompted us t...
ORGANISM(S): Mycobacterium tuberculosis H37Rv 
2018-09-25 | PXD010255 | Pride
Tuberculosis Lipolytic enzyme inhibitors Activity-based probe (abp) Oxadiazolone 
UnknownIdentification of motifs and mechanisms for lipid droplet targeting of the lipolytic inhibitors G0S2 and HIG2.
Not available
S-EPMC10112975 | biostudies-literature
UnknownIdentification of palmitoyl protein thioesterase 1 in human THP1 monocytes and macrophages and characterization of unique biochemical activities for this enzyme.
Not available
S-EPMC4102699 | biostudies-literature
UnknownFunctional annotation of serine hydrolases in the asexual erythrocytic stage of Plasmodium falciparum.
Not available
S-EPMC6879560 | biostudies-literature
ProteomicsANGPTL3/8 is an atypical unfoldase that regulates intravascular lipolysis by catalyzing unfolding of lipoprotein lipase as measured by hydrogen/deuterium exchange mass spectrometry (HDX-MS)
Lipoprotein lipase (LPL) carries out the lipolytic processing of triglyceride-rich lipoproteins (TRL) along the luminal surface of capillaries. LPL activity is regulated by angiopoietin-like proteins (ANGPTL3, ANGPTL4, and ANGPTL8), which control the delivery of TRL-derived lipid nutrients to tissue...
ORGANISM(S): Bos taurus (Bovine) Homo sapiens (Human) 
2025-03-26 | PXD060125 | Pride
Gpihbp1 Angptl3/8 Lipoprotein lipase Intravascular lipolysis Hdx-ms 
UnknownAdipose Triglyceride Lipase Is a Therapeutic Target in Advanced Prostate Cancer That Promotes Metabolic Plasticity.
Not available
S-EPMC10939928 | biostudies-literature
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