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ProteomicsLipoylated proteins complex in mouse brown adipose tissue
Immunoprecipitation of lipoic acid followed by mass spectrometry analysis to identify the lipoylated proteins complex in mouse brown adipose tissue.
ORGANISM(S): Mus musculus (Mouse) 
2019-07-17 | PXD014080 | Pride
Lipoylated protein Brown adipose tissue Mouse 
UnknownCopper induces cell death by targeting lipoylated TCA cycle proteins.
Not available
S-EPMC9273333 | biostudies-literature
ProteomicsChemical Tagging of Protein Lipoylation
Protein lipoylation is a post-translational modification of emerging importance in both prokaryotes and eukaryotes. However, effective methods for labeling and analyzing, particularly in large scale, protein lipoylation remain limited. Here, we report the development of iLCL (iodoacetamide-assisted ...
ORGANISM(S): Mus musculus (Mouse) Escherichia coli 
2020-11-16 | PXD021948 | Pride
Chemical proteomics Chemoselective ligation Lipoylation 
UnknownA Lipoylated Metabolic Protein Released by Staphylococcus aureus Suppresses Macrophage Activation.
Not available
S-EPMC5683407 | biostudies-literature
UnknownStructure of the sirtuin-linked macrodomain SAV0325 from Staphylococcus aureus.
Not available
S-EPMC5338245 | biostudies-literature
ProteomicsQuantitative Site-specific Chemoproteomic Profiling of Protein Lipoylation
Protein lipoylation is an evolutionarily conserved post-translational modification (PTM) from prokaryotes and eukary-otes. Lipoylation is known to contribute to several human diseases including metabolic disorders, cancer and Alz-heimer’s disease. While individual lipoylated proteins have been bioch...
ORGANISM(S): Homo Sapiens Escherichia Coli 
2022-02-05 | PXD031466 |
UnknownChemoselective and laser cleavable probes for <i>in situ</i> protein lipoylation detection by laser desorption/ionization mass spectrometry.
Not available
S-EPMC11808561 | biostudies-literature
MetabolomicsABHD11/ROLIP maintains the TCA cycle by preserving functional lipoylation of the 2-oxoglutarate dehydrogenase complex
2-oxoglutarate (2-OG) relates mitochondrial metabolism to cell function: conversion of 2-OG to succinyl-CoA by the 2-OG dehydrogenase complex (OGDHc) is rate-limiting for the Tricarboxylic Acid (TCA) cycle, but 2-OG is also required for oxygen sensitive enzymes (2-OG dependent dioxygenases) that hav...
2020-08-10 | MTBLS1875 | MetaboLights
UnknownProtein-protein interaction based substrate control in the E. coli octanoic acid transferase, LipB.
Not available
S-EPMC8495967 | biostudies-literature
UnknownOhr (organic hydroperoxide resistance protein) possesses a previously undescribed activity, lipoyl-dependent peroxidase.
Not available
S-EPMC2903379 | biostudies-literature
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