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MALT1 protease inhibition is effective in several preclinical models of autoimmunity and B cell malignancies. However, severe reduction in regulatory T cells (Tregs) and an associated IPEX-like pathology was observed in mice with congenital deficiency of MALT1. Rats treated with MLT-943, a novel pot...
ORGANISM(S): Rattus norvegicus 
We profiled gene expression and splicing changes in MCF-10A human mammary epithelial cells expressing MYC fused to a portion of estrogen receptor (MYC-ER) (Eilers et al., 1989; Littlewood et al., 1995). We performed RNA-seq, in triplicate, on 3D-grown MCF-10A MYC-ER cells at 0, 8, and 24 hours (h) a...
ORGANISM(S): Homo sapiens 
2022-07-11 | GSE181968 | GEO
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