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UnknownAberrant DNA Methylation of P16, MGMT, and hMLH1 Genes in Combination with MTHFR C677T Genetic Polymorphism in gastric cancer.
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S-EPMC3905372 | biostudies-literature
MetabolomicsPuerarin Combined with Hericium Erinaceus Insoluble Dietary Fiber Alleviate Obesity Induced by High-fat Diet Through Regulating the Glycerophospholipid Metabolism Pathway Influenced by Gut Microbiota
The combination of HEIDF and Pue holds significant importance in the context of obesity. This synergistic effect not only aids in weight management but may also enhance metabolic health through various mechanisms, including increased satiety and promotion of fat oxidation. Therefore, incorporating t...
2025-02-17 | MTBLS12195 | MetaboLights
ProteomicsProteomics analysis report of cucumber root
Discovering the mechanism by which CO2 enrichment alleviates drought stress in the roots of cucumber seedlings via proteomic analysis
ORGANISM(S): Cucumis Sativus 
2022-01-26 | PXD031284 |
ProteomicsIdentification of Key Proteins and Pathways in Myocardial Infarction Using Machine Learning Approaches
Acute myocardial infarction (AMI) is a leading cause of global morbidity and mortality, requiring deeper insights into its molecular mechanisms for improved diagnosis and treatment. This study combines proteomics, multi-omics, and machine learning (ML) to identify key proteins and pathways associate...
ORGANISM(S): Homo Sapiens 
PXD062794 |
Proteomicsdevelopment of prognostic biomarkers for HBV-related acute-on-chronic liver failure
development of prognostic biomarkers for HBV-related acute-on-chronic liver failure
ORGANISM(S): Homo Sapiens 
2020-03-07 | PXD017928 |
ProteomicsBlood and Urine-Based Liquid Biopsy for early stage cancer investigation: Taken Clear Renal Cell Carcinoma as A Model
We analyzed samples of tumor tissue, plasma, and urine from a cohort of 27 ccRCC patients with T1-2 stage and 27 matched healthy controls, using liquid chromatography–mass spectrometry (LC-MS) for proteomic analysis. We integrated the differential proteins found in the three types of samples to expl...
ORGANISM(S): Homo Sapiens 
2023-06-20 | PXD043118 |
ProteomicsLysine methylation promotes NFAT5 activation upon EGFR activation and predicts response to temozolomide
Temozolomide (TMZ) therapy offers minimal clinical benefits in patients with glioblastoma multiforme (GBM) with high EGFR activity, underscoring the need for effective combination therapy. Here, we show that tonicity-responsive enhancer binding protein (NFAT5) lysine methylation, is a determinant of...
ORGANISM(S): Homo Sapiens 
2022-11-01 | PXD037869 |
TranscriptomicsTreatment of myeloma cell lines with the bromodomain inhibitor I-BET151
KMS12BM and H929 myeloma cells were treated in vitro with either I-BET151 1uM or vehicle (DMSO) for 6 hours (n=3 independent experiments for each cell line). Total RNA was extracted from H929 and KMS12BM cells using the RNeasy Mini kit (Qiagen). Genomic DNA contamination was eliminated using colum...
ORGANISM(S): Homo sapiens 
2013-12-22 | E-MTAB-2122 | biostudies-arrayexpress
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