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UnknownIL-1β receptor antagonist (IL-1Ra) combined with autophagy inducer (TAT-Beclin1) is an effective alternative for attenuating extracellular matrix degradation in rat and human osteoarthritis chondrocytes.
Not available
S-EPMC6617669 | biostudies-literature
ProteomicsThe novels biomarkers for assessing clinical benefits of continuous renal replacement therapy in pediatric sepsis
Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection. Continuous renal replacement therapy (CRRT) is regarded as an adjuvant therapy for critically ill, which removes excess fluids and clear uremic toxins, endotoxins, proteins, and inflammatory mediators...
ORGANISM(S): Homo Sapiens 
2022-03-25 | PXD032807 |
UnknownThe Involvement of Mutual Inhibition of ERK and mTOR in PLCγ1-Mediated MMP-13 Expression in Human Osteoarthritis Chondrocytes.
Not available
S-EPMC4576213 | biostudies-literature
ProteomicsRevealing proteome characteristics and disease treatment potential of different batches of hUC-MSC-Exo based on LC-MS/MS
As an important part of regenerative medicine, human umbilical cord mesenchymal stem cells show a good clinical therapeutic effect, but their use is still limited. In recent years, the use of umbilical cord mesenchymal stem cell exosomes as cell replacement therapy can effectively overcome some defe...
ORGANISM(S): Mus Musculus 
2022-11-01 | PXD037877 |
ProteomicsThe Glomerulus Multi-Omics Analysis Provides Deeper Insights into Diabetic Nephropathy
Diabetic nephropathy (DN) is the leading cause of end-stage renal disease (ESRD), however, the detail mechanisms remain unclear. Here, we integrated the transcriptomics and proteomics profiles of glomeruli isolated from 50 biopsy-proven DN patients and 25 controls to explore the new discoveries unde...
ORGANISM(S): Homo Sapiens 
2023-03-06 | PXD040617 |
TranscriptomicsGenome-wide detection by array CGH of copy number variations among diverse horse breeds
Investigating genome-wide characteristics of CNVs in 6 horses representing 6 distinct breeds by using the aCGH method and performed GO and KEGG analysis for the CNVs genes.This result is an important complement to the mapping of horse whole-genome CNVs and helpful to study plateau horsesM-bM-^@M-^Y ...
ORGANISM(S): Equus caballus 
2014-02-26 | E-GEOD-52504 | biostudies-arrayexpress
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