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MetabolomicsLipid-accumulated reactive astrocytes promote disease progression in epilepsy (Human lipidomics)

Reactive astrocytes play an important role in neurological diseases, but their molecular and functional phenotypes in epilepsy are unclear. Here, we show that in patients with temporal lobe epilepsy (TLE) and mouse models of epilepsy, excessive lipid accumulation in astrocytes leads to the format...

2025-07-03 | MTBLS8856 | MetaboLights
MetabolomicsLipid-accumulated reactive astrocytes promote disease progression in epilepsy (Mice lipidomics)

Reactive astrocytes play an important role in neurological diseases, but their molecular and functional phenotypes in epilepsy are unclear. Here, we show that in patients with temporal lobe epilepsy (TLE) and mouse models of epilepsy, excessive lipid accumulation in astrocytes leads to the format...

2025-07-04 | MTBLS8865 | MetaboLights
ProteomicsMulti-organ proteomic and phosphoproteomic landscape of K18-hACE2 mice infected with SARS-CoV-2
Eight 10-week-old female K18-hACE2 mice were equally divided into control (n = 4) and virus-infected group (n = 4). Mice in the virus-infected group were challenged with 10^5 median tissue culture infective dose (TCID50) of SARS-CoV-2 virus by intranasal inoculation and mice in the control group wer...
ORGANISM(S): Mus Musculus 
2022-07-21 | PXD035474 |
UnknownAssemblathon 2: evaluating de novo methods of genome assembly in three vertebrate species.
Not available
S-EPMC3844414 | biostudies-literature
UnknownThe Genetic Architecture of Depression in Individuals of East Asian Ancestry: A Genome-Wide Association Study.
Not available
S-EPMC8482304 | biostudies-literature
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