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TranscriptomicsBacterial Adaptation Through Loss of Function
Transcriptional profiling of mutants with beneficial in-frame null mutations. The goal of the study is to understand how expression of the mutants and their parental strain differs in conditions where the mutations are beneficial. For each of two conditions (media with either glutamine or alanine a...
ORGANISM(S): Escherichia coli str. K-12 substr. MG1655 
2013-08-23 | E-GEOD-30345 | biostudies-arrayexpress
ProteomicsMICU3 Plays an Important Role in Cardiovascular Function
Mitochondrial calcium regulates bioenergetics but also serves as a trigger for cell death.1 With a sustained increase in catecholamine or a large increase in cytosolic calcium as occurs with ischemia, mitochondrial calcium can rise to high levels, leading to activation of the mitochondrial permeabil...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2021-11-23 | MSV000088439 | MassIVE
TranscriptomicsEstrogen-mediated Epigenetic Repression of Large Chromosomal Regions through DNA Looping
The current concept of epigenetic repression is based on one repressor unit corresponding to one silent gene. This notion, however, cannot adequately explain concurrent silencing of multiple loci observed in large chromosome regions. The long-range epigenetic silencing (LRES) can be a frequent occur...
ORGANISM(S): Homo sapiens 
2010-04-29 | E-GEOD-21068 | biostudies-arrayexpress
GenomicsEGAS00001000017-sc-20110505 - samples
Familial Melanoma Sequencing
EGAD00001000016 | EGA
GenomicsFamilial Melanoma Sequencing
In this experiment we have sequenced the exome of 15 individuals from eight families who have familial melanoma. By sequencing the exome we hope to be able to identify new genes that are associated with this disease.
EGAS00001000017 | EGA
UnknownA syndromic neurodevelopmental disorder caused by rare variants in PPFIA3.
Not available
S-EPMC10806447 | biostudies-literature
UnknownA genome-wide association study of anorexia nervosa suggests a risk locus implicated in dysregulated leptin signaling.
Not available
S-EPMC5476671 | biostudies-literature
UnknownEvidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index.
Not available
S-EPMC5114162 | biostudies-literature
UnknownMapping genomic loci implicates genes and synaptic biology in schizophrenia.
Not available
S-EPMC9392466 | biostudies-literature
UnknownUsing brain cell-type-specific protein interactomes to interpret neurodevelopmental genetic signals in schizophrenia.
Not available
S-EPMC10189495 | biostudies-literature
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