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Proteomicsquantitative proteomic analysis of phagocytes in oyster Crassostrea gigas
Invertebrates lack the adaptive immune system homologous to that of vertebrates, thus depend exceptionally on the innate immune system for the pathogen recognition and clearance. Phagocytes play a pivotal role in the innate immunity of invertebrates, but the molecular basis underlying their phagocyt...
ORGANISM(S): Crassostrea Gigas 
PXD009987 |
TranscriptomicsGene expression profiling of glioblastoma cell lines transfected with FGFR3-TACC3
Gene expression profiling of SNB19 and U251 glioblastoma cell lines transfected with the FGFR3-TACC3 fusion, FGFR3 wildtype and TACC3 wildtype constructs. SNB19 and U251 cells were transfected with different clones of the FGFR3-TACC3 fusion and with wildtype FGFR3 and TACC3 constructs. Total RNA was...
ORGANISM(S): Homo sapiens 
2012-12-01 | E-GEOD-42401 | biostudies-arrayexpress
UnknownP1118: LONGER FOLLOW-UP FROM THE PIVOTAL EPCORE NHL-1 TRIAL REAFFIRMS SUBCUTANEOUS EPCORITAMAB INDUCES DEEP, DURABLE COMPLETE REMISSIONS IN PATIENTS WITH RELAPSED/REFRACTORY LARGE B-CELL LYMPHOMA
Not available
S-EPMC10431155 | biostudies-literature
ProteomicsIdentification of discriminative plasma protein biomarkers for recent Mycobacterium tuberculosis infection
This project presents a data-independent acquisition mass spectrometry (DIA-MS)–based plasma proteomics dataset generated to identify protein biomarkers associated with recent Mycobacterium tuberculosis (M.tb) infection. The study aimed to characterize proteomic differences among individuals with r...
ORGANISM(S): Homo Sapiens 
2026-02-09 | PXD074267 |
TranscriptomicsIGFBP2 driven glioma progression is prevented by blocking a clinically significant network of integrin, ILK, and NK-kB
Insulin-like growth factor-binding protein 2 (IGFBP2) is increasingly recognized as a glioma oncogene, emerging as a target for therapeutic intervention. In this study, we used an integrative approach to characterizing the IGFBP2 network, combining transcriptional profiling of human glioma with vali...
ORGANISM(S): Homo sapiens 
2012-02-02 | E-GEOD-35467 | biostudies-arrayexpress
TranscriptomicsInsulin-like growth factor-binding protein 2 Induces Epithelial-mesenchymal Transition via Activation of NF-M-NM-:B Pathway in Pancreatic Ductal Adenocarcinoma
IGFBP2 has been shown to act as an oncogene augmenting tumor progression in a number of malignancies. We sought to investigate role of IGFBP2 and its related pathways in PDAC. Gene expression profiling were used to reveal the key signaling pathways. Microarray experiments in IGFBP2-overexpressing ...
ORGANISM(S): Homo sapiens 
2015-01-01 | E-GEOD-64611 | biostudies-arrayexpress
TranscriptomicsGene expression signatures of MEF2D-silencing hepatocellular carcinoma cells
Global expression profiles in Huh7 after infection with Lv-shMEF2D and Lv-scrambled, as well as transfection with siRNA-MEF2D and siRNA-control, were compared to investigate the molecular mechanisms involved in MEF2D-mediated regulation of cell cycle. In order to investigate the molecular mechanisms...
ORGANISM(S): Homo sapiens 
2015-04-07 | E-GEOD-37123 | biostudies-arrayexpress
TranscriptomicsThe tumorigenic fusion FGFR3-TACC3 escapes miR-99a regulation in glioblastoma
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2012-12-01 | E-GEOD-42402 | biostudies-arrayexpress
TranscriptomicsHigh resolution aCGH of the FGFR3-TACC3 locus in glioblastoma patients
Targeted high resolution array comparative genomic hybridization of the 4p16.3 locus in seven glioblastoma patients A custom Agilent CGH microarray based on the 105A backbone was designed with high probe coverage for 4p16.3. Tumor tissue from four FGFR3-TACC3 positive patients and three negative pat...
ORGANISM(S): Homo sapiens 
2012-12-01 | E-GEOD-42400 | biostudies-arrayexpress
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