Sort   by:  
 Page size 
GenomicsNOTCH1/RBPJ complexes drive target gene expression through dynamic interactions with super-enhancers
The main oncogenic driver in T-lymphoblastic leukemia (T-LL) is NOTCH1, which activates genes by forming chromatin-associated Notch transcription complexes. Gamma-secretase (GSI) inhibitor treatment prevents NOTCH1 nuclear localization, but most genes with NOTCH1 binding sites are insensitive to GSI...
ORGANISM(S): Homo sapiens 
2013-12-27 | E-GEOD-51800 | biostudies-arrayexpress
UnknownIntraoperative isotonic balanced versus hypotonic crystalloids on postoperative sodium homeostasis in small children undergoing major neurosurgery: a randomized controlled trial.
Not available
S-EPMC11909862 | biostudies-literature
UnknownConstruction of a high-density genetic map and dissection of genetic architecture of six agronomic traits in tobacco (Nicotiana tabacum L.).
Not available
S-EPMC9975568 | biostudies-literature
UnknownSingle-cell RNA sequencing reveals peripheral immunological features in Parkinson's Disease.
Not available
S-EPMC11452393 | biostudies-literature
UnknownOrgan-specific metastatic landscape dissects PD-(L)1 blockade efficacy in advanced non-small cell lung cancer: applicability from clinical trials to real-world practice.
Not available
S-EPMC9004108 | biostudies-literature
UnknownUnderlying features of epigenetic aging clocks in vivo and in vitro.
Not available
S-EPMC7576259 | biostudies-literature
UnknownDual-site molecular glues for enhancing protein-protein interactions of the CDK12-DDB1 complex.
Not available
S-EPMC11294606 | biostudies-literature
MetabolomicsCirculatory metabolomics reveals the association of the metabolites with clinical features in the patients with intrahepatic cholestasis of pregnancy

OBJECTIVE: Intrahepatic cholestasis of pregnancy (ICP) is associated with an increased risk of adverse pregnancy outcomes to the mother and fetus. As yet, the metabolic profiles and the association of the clinical features remain obscure.

METHODS: Fifty sev...

2022-03-01 | MTBLS2627 | MetaboLights
UnknownNon-HDL-C Is More Stable Than LDL-C in Assessing the Percent Attainment of Non-fasting Lipid for Coronary Heart Disease Patients.
Not available
S-EPMC8049565 | biostudies-literature
ProteomicsHRD1 IP-MS in WT and SEL1L deficiency HEK293T cells
To gain further insights into the role and importance of SEL1L in HRD1 ERAD, we performed unbiased proteomics LC-MS analyses to map SEL1L and HRD1 interactomes in WT and SEL1L-/-, WT and HRD1-/- HEK293T cells, respectively.
ORGANISM(S): Homo sapiens (Human) 
2024-01-10 | PXD043674 | Pride
Erad complex formation Sel1l-hrd1 erad Hek293t 
Sort   by:  
 Page size