Sort   by:  
 Page size 
ProteomicsComprehensive understanding the molecular components of LTBR signalling complex in cancers
Lymphotoxin beta receptor (LTBR), a member of TNFRSF, was identified as a key regulator in the development, organization, and homeostasis of lymphoid tissues (Wolf, Seleznik, Zeller, & Heikenwalder, 2010). Recently, LTBR has been shown to play a role in tumor biology, both in solid tumors and in hem...
ORGANISM(S): Homo sapiens (Human) 
2025-04-01 | PXD034142 | Pride
Human Ap-ms Lc-ms Lfq 
UnknownRandomized phase II study of erlotinib in combination with placebo or R1507, a monoclonal antibody to insulin-like growth factor-1 receptor, for advanced-stage non-small-cell lung cancer.
Not available
S-EPMC5320944 | biostudies-literature
TranscriptomicsTranscription profiling of human breast cancer cell lines and tissue samples to identify aberrant microRNA expression
MicroRNAs are a class of small non-coding RNAs that control gene expression by targeting messenger RNAs and triggering either translation repression or RNA degradation. Their aberrant expression may be involved in human diseases, including cancer. Indeed, microRNA aberrant expression has been previo...
ORGANISM(S): Homo sapiens 
2006-01-01 | E-TABM-23 | biostudies-arrayexpress
MetabolomicsUntargeted Metabolomics Reveals Molecular Effects of Ketogenic Diet on Healthy and Tumor Xenograft Mouse Models
The application of ketogenic diet (KD) (high fat/low carbohydrate/adequate protein) as an auxiliary cancer therapy is a field of growing attention. KD provides sufficient energy supply for healthy cells, while possibly impairing energy production in highly glycolytic tumor cells. Moreover, KD regula...
2019-10-08 | MTBLS1066 | MetaboLights
ModelsRahman2022 - High throughput antibacterial screening with machine learning.
Prediction of antimicrobial potential using a dataset of 29537 compounds screened against the antibiotic resistant pathogen Burkholderia cenocepacia. The model uses the Chemprop Direct Message Passing Neural Network (D-MPNN) and has an AUC score of 0.823 for the test set. It has been used to virtual...
2024-04-22 | MODEL2404080002 | BioModels
Machine Learning Model Ersilia 
ProteomicsSerum integrative omics reveals the landscape of human diabetic kidney disease
Diabetic kidney disease (DKD) is the most common microvascular complication of type 2 diabetes mellitus (2-DM). Currently, urine and kidney biopsy specimens are the major clinical resources for DKD diagnosis. The diagnostic values of blood in monitoring the onset and progression of DKD have not been...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-05-22 | MSV000087487 | MassIVE
ProteomicsTargeted and non-targeted mass spectrometry to explore the chemical diversity of the genus Gambierdiscus in the Atlantic Ocean
The 15 strains of Gambierdiscus were cultivated in four separate laboratories. Each laboratory grew their available strains (see sample metadata) in addition to the G. australes strain AUS S080911_1 isolated from Pacific Ocean. Irradiance (70-100 umol photons m-2 s-1) and light/dark cycle (12h:12h)...
ORGANISM(S): Gambierdiscus Silvae (ncbitaxon:1550089) Gambierdiscus Carolinianus (ncbitaxon:864182) Gambierdiscus Australes (ncbitaxon:439317) Gambierdiscus Belizeanus (ncbitaxon:439316) Gambierdiscus Excentricus (ncbitaxon:986170) Gambierdiscus Caribaeus (ncbitaxon:864185) 
2024-02-26 | MSV000094172 | MassIVE
TranscriptomicsHuman T cells isolated from healthy European and African American blood donors: Control vs. Interferon alpha 2b-treated
Transcriptional profiling of human T cells analyzing the impact of race on the responsiveness to IFNa in healthy blood donors. Control and IFNa-treated samples derived from healthy Caucasian American vs. African American blood donors are compared. Two-condition experiment, Control vs. IFNa-treated. ...
ORGANISM(S): Homo sapiens 
2010-05-16 | E-GEOD-17952 | biostudies-arrayexpress
MetabolomicsFSCN1 as a new druggable target in adrenocortical carcinoma

Adrenocortical carcinoma (ACC) is a rare endocrine malignancy with a high risk of relapse and metastatisation. The actin-bundling protein fascin (FSCN1) is overexpressed in aggressive ACC and represents a reliable prognostic indicator. FSCN1 has been shown to synergize with the Rho/Rac GEF VAV2 i...

2023-03-20 | MTBLS6402 | MetaboLights
MetabolomicsGNPS - Serum integrative omics reveals the landscape of human diabetic kidney disease
Diabetic kidney disease (DKD) is the most common microvascular complication of type 2 diabetes mellitus (2-DM). Currently, urine and kidney biopsy specimens are the major clinical resources for DKD diagnosis. The diagnostic values of blood in monitoring the onset and progression of DKD have not been...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-05-22 | MSV000087487 | GNPS
Sort   by:  
 Page size