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MetabolomicsTidal filtering drives microbiome assembly and metabolic coupling in desiccation-tolerant red algae


This study investigates how the intertidal red alga Pyropia haitanensis (Bangiophyceae) achieves rapid desiccation-rehydration tolerance through coordinated interactions between the host, its associated microbiome, and key metabolites. By integrating 16S rRNA amplicon sequencing, metag...

2026-05-07 | MTBLS13613 | MetaboLights
MetabolomicsL-fucose and fucoidan alleviate high-salt diet-promoted acute inflammation

Excessive salt intake is a widespread health issue observed in almost every country around the world. A high salt diet (HSD) has a strong correlation with numerous diseases, including hypertension, chronic kidney disease and autoimmune disorders. However, the mechanisms underlying HSD-promotion o...

2024-02-21 | MTBLS9134 | MetaboLights
TranscriptomicsMicroarray skeletal muscle miR-499 overexpressing mice
This experiment was conducted to identify target genes of the microRNA-499 in skeletal muscle of transgenic mice that overexpressed miR-499. The following abstract from the submitted manuscript describes the major findings of this work. Coupling of mitochondrial function and skeletal muscle f...
ORGANISM(S): Mus musculus 
2016-09-03 | E-GEOD-72581 | biostudies-arrayexpress
MetabolomicsMetabolomic analysis of alfalfa (Medicago sativa L.) root-symbiotic rhizobia responses under alkali stress
Alkaline salts (e.g., NaHCO3 and Na2CO3) causes more severe morphological and physiological damage to plants than neutral salts (e.g., NaCl and Na2SO4) due to differences in pH. The mechanism by which plants respond to alkali stress is not fully understood, especially in plants having symbotic relat...
2018-07-27 | MTBLS481 | MetaboLights
TranscriptomicsFetal lung development
Fetal lung development is a complex biological process, which involves temporal and spatial regulations of many genes. To understand molecular mechanisms of this process, we investigated gene expression profiling of lungs at gestational day 18, 19, 20, 21, new born, and adult rats using in-house rat...
ORGANISM(S): Rattus norvegicus 
2010-07-01 | E-GEOD-3302 | biostudies-arrayexpress
TranscriptomicsLong non-coding RNAs are differentially expressed in hepatocellular carcinoma cell lines with different metastatic potential
We describe the lncRNA expression profiles of two HCC cell lines, one with high potential for metastasis to the lung (HCCLM3) and the other to lymph nodes (HCCLYM-H2). The HCCLM3(LM3) and HCCLM6 cell lines were derived from the same parental cell line MHCC-97H. LM3 metastasizes to the lung, while HC...
ORGANISM(S): Homo sapiens 
2014-09-03 | E-GEOD-61015 | biostudies-arrayexpress
TranscriptomicsMicroRNA signatures in human cervical cancer
Our study investigates miRNAs might play a role in the pathogenesis of cervical cancer and identify altered miRNA gene methylation as a possible epigenetic mechanism involved in their aberrant expression. Cervical cancer cells were seeded at low density and cultured for 48 h. Experimental groups wer...
ORGANISM(S): Homo sapiens 
2011-10-10 | E-GEOD-32724 | biostudies-arrayexpress
UnknownProtein phosphatase 4 promotes Hedgehog signaling through dephosphorylation of Suppressor of fused.
Not available
S-EPMC7442787 | biostudies-literature
TranscriptomicsDGE analysis of transcriptome change during photoperiodic regulation of potato tuber formation
We analyzed the transcriptome change during photoperiodic regulation of potato tuber formation 3 samples from longday condition and 2 samples from shortday condition were sequenced
ORGANISM(S): Solanum tuberosum 
2014-03-20 | E-GEOD-45008 | biostudies-arrayexpress
ProteomicsBartonella VBNC formation and resuscitation
DIA proteomic analysis of temp induced VBNC Bartonella henselae
ORGANISM(S): Bartonella Henselae Str. Houston-1 
PXD055316 |
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