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Human embryonic stem cells (hESCs) exhibit a skewed X chromosome inactivation (XCI) have recently been reported. Whether there is any copy number variation (CNV), loss of heterozygousity (LOH) and single nucleotide variant (SNV) in those epigenetically distinct cells and whether these abnormalities ...
ORGANISM(S): Homo sapiens 
Recent studies have shown a close relationship between the gut microbiota and Crohn's disease (CD). This study aimed to determine whether mesenchymal stem cell (MSC) treatment alters the gut microbiota and fecal metabolite pathways and to establish the relationship between the gut microbiota and fec...
2025-07-03 | MTBLS6288 | MetaboLights
LC-MS/MS was used to carry out the analysis of the crotonylome in C. albicans (Candida albicans) comprehensively in our study. Generally, 5242 specific crotonylated sites of 1584 crotonylated proteins were detected among 9038 proteins in C. albicans. The crotonylome involved in the regulation of met...
ORGANISM(S): Candida albicans (Yeast) 
2021-01-08 | PXD018848 | Pride
Family with sequence similarity 20-member C (FAM20C) is a new molecule that is highly expressed in the mineralized tissues of mammals. Genetic studies showed that the loss-of-function mutations in FAM20C were associated with human lethal osteosclerotic bone dysplasia (Raine Syndrome), indicating tha...
ORGANISM(S): Mus musculus 
Autologous nonmyeloablative hematopoietic stem cell transplantation (AHST) was the first therapeutic approaches that can improve beta cell function in type 1 diabetic (T1D) patients. This study was designed to investigate the potential mechanisms involved.We applied AHST to nine T1D patients diagnos...
ORGANISM(S): Homo sapiens 
To screen serum molecular markers systematically amid aortic dissection and acute coronary syndrome, preliminary identify the pathogenesis of acute aortic dissection.
ORGANISM(S): Homo Sapiens 
2022-03-25 | PXD032857 |
HDCA supplementation ameliorated diet-induced NAFLD in C57 wild type mice. In attempt to comprehensively understand the molecular mechanism occurring during the protective effect of HDCA, transcriptomic and proteomic profiles of mouse liver were first analyzed utilizing RNA-Sequencing and Tandem Mas...
ORGANISM(S): Mus Musculus 
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