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ProteomicsAltered profile of glycosylated proteins in serum samples obtained from patients with Hashimoto′s thyroiditis following depletion of highly abundant proteins
Objectives: Hashimoto’s thyroiditis (HT) is one of the most common autoimmune disorders; however, its underlying pathological mechanisms remain unclear. Although aberrant glycosylation has been implicated in the N-glycome of immunoglobulin G (IgG), changes in serum proteins have not been comprehensi...
ORGANISM(S): Homo sapiens (Human) 
2023-06-22 | PXD040847 | Pride
Glycosylation Ltf Masp-1 Lectin microarray Vva Hashimoto′s thyroiditis 
UnknownMicro-nanofiber composite biomimetic conduits promote long-gap peripheral nerve regeneration in canine models.
Not available
S-EPMC10406865 | biostudies-literature
ProteomicsLong-lived proteins and DNA as candidate predictive biomarkers for tissue associated diseases
Protein turnover, the result of protein synthesis and degradation, is an important mechanism to preserve cellular integrity. The majority of cellular proteins are broken down over a period of hours to weeks to prevent a buildup of proteins that lose their function due to damage caused by misfolding,...
ORGANISM(S): Mus Musculus 
2024-03-21 | PXD050843 |
ProteomicsTransketolase promotes MAFLD by limiting inosine-induced mitochondrial activity (Proteomics)
Metabolic dysfunction-associated fatty liver disease (MAFLD) has a global prevalence of about 25% and no approved therapy. Using metabolomic and proteomic analyses, we identified high expression of hepatic transketolase (TKT), a metabolic enzyme of the pentose phosphate pathway, in human and mouse M...
ORGANISM(S): Homo Sapiens 
2024-02-26 | PXD050130 |
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