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MetabolomicsMetabolomic Profiling of Mice Serum during Toxoplasmosis Progression Using Liquid Chromatography-Mass Spectrometry
Better understanding of the molecular changes associated with disease is essential for identifying new routes to improved therapeutics and diagnostic tests. The aim of this study was to investigate the dynamic changes in the metabolic profile of mouse sera during T. gondii infection. We carried out ...
2017-01-25 | MTBLS216 | MetaboLights
MetabolomicsGlobal Metabolomic Profiling of Mice Brains following Experimental Infection with the Cyst-Forming Toxoplasma gondii
The interplay between the Apicomplexan parasite Toxoplasma gondii and its host has been largely studied. However, molecular changes at the metabolic level in the host central nervous system and pathogenesis-associated metabolites during brain infection are largely unexplored. We used a global metabo...
2017-01-27 | MTBLS217 | MetaboLights
MetabolomicsSulfadiazine Sodium Improves Dysfunctional Metabolomics in Toxoplasma gondii-infected Mice
Toxoplasma gondii is an obligate intracellular protozoan parasite that poses a severe threat to human health, especially those immune-compromised individuals. Sulfadiazine sodium (SDZ) is widely used for the treatment of human toxoplasmosis. However, systems biology researches on the therapeutic eff...
2019-06-18 | MTBLS852 | MetaboLights
MetabolomicsSerum Metabolic Profiling of Oocyst-Induced Toxoplasma gondii Acute and Chronic Infections in Mice Using Mass-Spectrometry
Toxoplasma gondii is an obligate intracellular parasite causing severe diseases in immunocompromised individuals and congenitally infected neonates, such as encephalitis and chorioretinitis. This study aimed to determine whether serum metabolic profiling can (i) identify metabolites associated with ...
2018-04-16 | MTBLS418 | MetaboLights
UnknownClinical characteristics and related risk factors of disease severity in 101 COVID-19 patients hospitalized in Wuhan, China.
Not available
S-EPMC7976686 | biostudies-literature
UnknownRelationship between serum uric acid, all-cause mortality and cardiovascular mortality in peritoneal dialysis patients: systematic review and meta-analysis of cohort studies.
Not available
S-EPMC8524295 | biostudies-literature
UnknownEffect of dietary L-glutamate levels on growth, digestive and absorptive capability, and intestinal physical barrier function in Jian carp (Cyprinus carpio var. Jian).
Not available
S-EPMC7283372 | biostudies-literature
UnknownHigher risk of postpartum phase transition to immune-active among HBeAg-positive pregnant women with indeterminate phase.
Not available
S-EPMC12819656 | biostudies-literature
UnknownCardiotoxicity as indicated by LVEF and troponin T sensitivity following two anthracycline-based regimens in lymphoma: Results from a randomized prospective clinical trial.
Not available
S-EPMC5078030 | biostudies-literature
UnknownIL-6 knockdown anti-CD19 CAR-T cells (ssCART-19) for patients with relapsed or refractory acute lymphoblastic leukemia: phase 1 trial.
Not available
S-EPMC12559308 | biostudies-literature
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