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TranscriptomicsGene expression signatures for murine alveolar type II lung epithelial cells after tumor bearing
To determine the influence of primary tumors on pre-metastatic lungs, we have employed whole genome microarray expression profiling as a discovery platform to identify gene signatures of alveolar type II epithelial cells (AT-II) in TLR3 deficient mice (Tlr3-/-) and wide-type (WT) littermates with tu...
ORGANISM(S): Mus musculus 
2016-08-10 | E-GEOD-76397 | biostudies-arrayexpress
TranscriptomicsRNA Sequencing Analysis of Mouse Bone Marrow Derived Dendritic Cells Transcriptomes During Maturation
Purpose:The purpose of this study is to detect activated or silenced genes during LPS-induced dendritic cell maturation. Gene expression differences between two samples could be found using transcriptome profiling (RNA-seq) analysis. Methods:Mouse dendritic cells were generated from bone marrow cell...
ORGANISM(S): Mus musculus 
2015-03-04 | E-GEOD-60307 | biostudies-arrayexpress
TranscriptomicsGene expression signatures for primary tumor and tumor-derived exosomes
To determine the different gene signatures between primary tumor and tumor-derived exosomes, we have employed RNA-sequencing as a discovery platform to identify gene signatures of tumor-derived exosomes, taking the original tumors as a control. We subcutaneously inoculated C57BL/6 mice with Lewis lu...
ORGANISM(S): Mus musculus 
2016-08-10 | E-GEOD-80678 | biostudies-arrayexpress
TranscriptomicsNext Generation Sequencing Facilitates Quantitative Analysis of dendritic cell Transcriptomes during LPS response
Purpose:The purpose of this study is to detect activated or silenced genes during LPS-induced dendritic cell. Gene expression differences between two samples could be found using transcriptome profiling (RNA-seq) analysis. Methods:Mouse dendritic cells were generated from bone marrow cells in RPMI-...
ORGANISM(S): Mus musculus 
2015-09-11 | E-GEOD-69256 | biostudies-arrayexpress
ProteomicsIdentification of proteins associated with IFN-γR2 in macrophages
Department of Immunology & Center for Immunotherapy
ORGANISM(S): Mus Musculus 
2018-10-25 | PXD011572 |
TranscriptomicsDC-specific lincRNA controls dendritic cell development and function through interacting with STAT3
To identify the functional non-coding RNAs in human DC development, we explored the gene expression profiles during DC development from peripheral monocytes. Using microarray technique, we identified many annotated lncRNAs with markedly altered expressions during human DC differentiation and maturat...
ORGANISM(S): Homo sapiens 
2014-05-02 | E-GEOD-54143 | biostudies-arrayexpress
TranscriptomicsGenomic expression analysis of human monocyte-derived DCs and monocytes
To identify the functional non-coding RNAs in human DC development, we explored the gene expression profiles during DC development from peripheral monocytes. Using RNA-seq, we identified many annotated lncRNAs with markedly altered expressions during human DC differentiation and maturation. RNA samp...
ORGANISM(S): Homo sapiens 
2014-05-02 | E-GEOD-54401 | biostudies-arrayexpress
ProteomicsPhosphorylated TLR3 nuclear translocation in cancer cell promotes metastasis and chemoresistance
Phosphorylated TLR3 nuclear translocation in cancer cell promotes metastasis and chemoresistance
ORGANISM(S): Homo Sapiens 
2025-06-07 | PXD064767 |
ProteomicsMass spectrometry to analyse expressed proteins in Panc1 with or without siRNA silencing PRMT5
Mass spectrometry to analyse expressed proteins in Panc1 with or without siRNA silencing PRMT5
ORGANISM(S): Homo Sapiens 
2025-06-07 | PXD064762 |
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