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Gallstones are crystalline deposits in the gallbladder that are traditionally classified as cholesterol, pigment or mixed stones based on their composition. Microbiota and host metabolism variances among the different types of gallstones remain largely unclear. Here, the bile and gallstone microb...

2024-03-11 | MTBLS7736 | MetaboLights

Mature milk, as a nutrient-rich endogenous metabolite, has various beneficial effects on the human body. In order to investigate the specific nutrients provided by different dairy products to humans, we used UHPLC-Q-TOF MS to analyze the highly significantly differentially expressed metabolites i...

2023-08-21 | MTBLS6777 | MetaboLights
The N6-methyladenosine (m6A) is the most abundant internal modification in almost all eukaryotic messenger RNAs, and is dynamically regulated. Therefore, identification of m6A readers is especially important in determining the cellular function of m6A. YTHDF2 has recently been characterized as the f...
ORGANISM(S): Homo sapiens 
Results: Host-induced gene silencing (HIGS) of VdEGe1 in cotton significantly attenuated Verticillium wilt symptoms, reduced fungal biomass, and lowered disease indices. Deletion of VdEGe1 impaired colony expension, sporulation, and carbon source utilization, and led to a marked reduction in pathoge...
ORGANISM(S): Verticillium Dahliae Vdls.17 
2026-01-14 | PXD073085 |
We developed a vessel-on-a-chip to mimic both physiological and pathological stretch, along with a mouse model of hypertension. We applied proteomics analysis to investigate the changes in vascular smooth muscle cells using the vessel-on-a-chip system and changes in hypertensive mice.
ORGANISM(S): Mus Musculus 
2024-11-08 | PXD057724 |
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