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ProteomicsPhage depolymerase modulates virulence and biofilm in hypervirulent Klebsiella pneumoniae by CPS-mediated suppression of type 3 fimbriae
Phage-derived depolymerases represent a promising antibiotic alternative for treating Klebsiella pneumoniae infections. Depolymerases can increase the sensitivity of bacteria to the host immune system and complement-mediated killing by specifically degrading capsular polysaccharides (CPS). However, ...
ORGANISM(S): Homo sapiens (Human) Klebsiella pneumoniae 
2026-06-28 | PXD080233 | Pride
Klebsiella pneumoniae  capsular polysaccharides  type 3 fimbriae  depolymerase  virulence  biofilm 
UnknownSerum soluble LYVE1 is a promising non-invasive biomarker of renal fibrosis: a population-based retrospective cross-sectional study.
Not available
S-EPMC11217098 | biostudies-literature
UnknownMitochondrial copper overload promotes renal fibrosis via inhibiting pyruvate dehydrogenase activity.
Not available
S-EPMC11335263 | biostudies-literature
MetabolomicsExploring the gut microbiome and serum metabolome interplay in non-functioning pituitary neuroendocrine tumors.

The gut microbiome has emerged as a potential factor in cancer pathogenesis, but its role in non-functioning pituitary neuroendocrine tumors (NF-PitNETs) remains unclear. This study aimed to elucidate gut microbiome and metabolomic alterations in NF-PitNETs by comparing microbial diversity, patho...

2025-06-16 | MTBLS12328 | MetaboLights
UnknownReal-time monitoring of microdistribution of antibody-photon absorber conjugates during photoimmunotherapy in vivo.
Not available
S-EPMC5726775 | biostudies-literature
Unknown3D mesoscopic fluorescence tomography for imaging micro-distribution of antibody-photon absorber conjugates during near infrared photoimmunotherapy in vivo.
Not available
S-EPMC5972681 | biostudies-literature
UnknownElevated intracellular copper contributes a unique role to kidney fibrosis by lysyl oxidase mediated matrix crosslinking.
Not available
S-EPMC7109154 | biostudies-literature
MetabolomicsGNPS - Serum integrative omics reveals the landscape of human diabetic kidney disease
Diabetic kidney disease (DKD) is the most common microvascular complication of type 2 diabetes mellitus (2-DM). Currently, urine and kidney biopsy specimens are the major clinical resources for DKD diagnosis. The diagnostic values of blood in monitoring the onset and progression of DKD have not been...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-05-22 | MSV000087487 | GNPS
ProteomicsDIA proteomic profiling of dorsal skin from Dendrobium officinale polysaccharide-treated C57BL/6 mice
This project contains DIA-PASEF proteomics data generated from dorsal skin tissues of male C57BL/6 mice in a control group, a DHT-induced androgenetic alopecia (AGA) model group, and a Dendrobium officinale polysaccharide (DOP, 7.5 mg/mL)-treated group. The study was designed to investigate proteomi...
ORGANISM(S): Mus Musculus 
PXD077413 |
ProteomicsSerum integrative omics reveals the landscape of human diabetic kidney disease
Diabetic kidney disease (DKD) is the most common microvascular complication of type 2 diabetes mellitus (2-DM). Currently, urine and kidney biopsy specimens are the major clinical resources for DKD diagnosis. The diagnostic values of blood in monitoring the onset and progression of DKD have not been...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-05-22 | MSV000087487 | MassIVE
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