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TranscriptomicsOryza sativa Transcriptome or Gene expression
To investigate impacts of genome-wide loss of Cytosine methylation at CG sites (mCs) on global expression of protein-coding genes (henceforth referring to genes), we conducted deep RNA-seq analysis on OsMET1-2−/− relative to its sibling WT and heterozygote (OsMET1-2+/−), each with two biologic...
ORGANISM(S): Oryza sativa 
2014-08-09 | E-MTAB-4224 | biostudies-arrayexpress
UnknownMutation of a major CG methylase in rice causes genome-wide hypomethylation, dysregulated genome expression, and seedling lethality.
Not available
S-EPMC4115543 | biostudies-literature
TranscriptomicsA Novel Neuron-specific Histone H4K20 Demethylase LSD1n Promotes Transcriptional Elongation and is Essential for Learning and Memory
LSD1n regulates transcriptional elongation by removing H4K20 methylation. Identification of genome-wide binding sites of LSD1, and examination of the histone modifications upon LSD1n deletion in primary cortical neurons
ORGANISM(S): Mus musculus 
2015-07-27 | E-GEOD-63271 | biostudies-arrayexpress
TranscriptomicsLigand-Dependent Enhancer Activation Regulated by Topoisomerase-I Activity
The discovery that enhancers are regulated transcription units, encoding eRNAs, has raised new questions about the mechanisms of their activation. Here, we report an unexpected molecular mechanism that underlies ligand-dependent enhancer activation, based on DNA nicking to relieve torsional stress f...
ORGANISM(S): Homo sapiens 
2015-01-22 | E-GEOD-63202 | biostudies-arrayexpress
UnknownThe burden of injury in China, 1990-2017: findings from the Global Burden of Disease Study 2017.
Not available
S-EPMC6739690 | biostudies-literature
GenomicsEnhancer-bound LDB1 Regulates a Corticotrope Promoter Pausing Repression Program [ChIP-seq]
Substantial evidence supports the hypothesis that enhancers are critical regulators of cell type determination, orchestrating both positive and negative transcriptional programs; however, the basic mechanisms by which enhancers orchestrate interactions with cognate promoters during activation and re...
ORGANISM(S): Mus musculus 
2015-02-03 | E-GEOD-64483 | biostudies-arrayexpress
TranscriptomicsEnhancer-bound LDB1 Regulates a Corticotrope Promoter Pausing Repression Program [GRO-seq]
Substantial evidence supports the hypothesis that enhancers are critical regulators of cell type determination, orchestrating both positive and negative transcriptional programs; however, the basic mechanisms by which enhancers orchestrate interactions with cognate promoters during activation and re...
ORGANISM(S): Mus musculus 
2015-02-03 | E-GEOD-64515 | biostudies-arrayexpress
ProteomicsProteomics profiles of hearts from atrial fibrillation patients
This study using heart from atrial fibrillation patients performed proteomics
ORGANISM(S): Homo Sapiens 
2023-03-28 | PXD041147 |
ProteomicsProteomic analysis of giant panda testicular tissue
Proteomic analysis of giant panda testicular tissue of different age groups
ORGANISM(S): Ailuropoda Melanoleuca 
2024-03-27 | PXD051003 |
ProteomicsProteomic profiles of giant panda spermatozoa seminal plasma
proteomic differences of seminal plasma proteins between healthy and cryptorchidism and normal testis of giant pandas
ORGANISM(S): Ailuropoda Melanoleuca 
2024-03-28 | PXD051040 |
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