Liver sinusoidal endothelial cells

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Max-Planck-Institute for Biology of Ageing Joseph-Stelzmann-Str. 9b 50931 Cologne, Germany (1)
Proteome Research (AG Stühler) Institute of Molecular Medicine I Heinrich Heine University Düsseldorf Universitätsstraße 1 40225 Düsseldorf (1)
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Comparison of gene expression between Human umbilical vein endothelial cells and Human liver sinusoidal endothelial cells

To identify leukocyte adhesion receptors which differentially regulate recruitment in human liver sinusoidal endothelial cells compared to a protoptypic venular endothelium Gene expression was measured in four groups Group 1: cultured human liver sinusoidal endothelial cells (HSEC) Group 2: cultured...

ORGANISM(S): Homo sapiens

2016-10-24 | E-GEOD-78020 | biostudies-arrayexpress

Normal and injured liver sinusoidal endothelial cells

Comparison of C57BL/6J 8-10 weeks male mouse liver sinusoidal endothelial cells (LSEC) from normal liver and from liver injured by carbon tetrachloride administration. Keywords: other

ORGANISM(S): Mus musculus

2004-10-01 | E-GEOD-1689 | biostudies-arrayexpress

Chemerin sustains the growth of spongiotrophoblast and sinusoidal trophoblast giant cells through fatty acid oxidation

Background: Placental metabolic abnormalities are linked to pregnancy complications such as preeclampsia, gestational diabetes mellitus and fetal growth restriction. However, little is known about how the metabolic processes regulate placental development and trophoblast differentiation. The adip...

2025-06-13 | MTBLS12552 | MetaboLights

Liver sinusoidal endothelial cells constitute a major route for hemoglobin clearance

Mild hemolysis of senescent erythrocytes occurs physiologically in the spleen resulting in Hb release, whereas pathologic erythrocyte rupture characterizes several diseases. Iron recycling from Hb and Hb detoxification have been attributed to the sequestration of Hb-haptoglobin complexes by macropha...

ORGANISM(S): Mus musculus (Mouse)

2025-11-12 | PXD051274 | Pride

VEGF-A stimulated gene expression in human liver sinusoidal endothelial cells

Transcriptomic analysis of VEGF-A stimulated liver sinusoidal endothelial cell gene expression. Untreated cells were compared to those treated with VEGF-A. VEGF-A stimulation is critical for normal LSEC phenotype, and the response to liver injury Two conditions: untreated vs. VEGF-A treated. LSEC...

ORGANISM(S): Homo sapiens

2013-06-01 | E-GEOD-41110 | biostudies-arrayexpress

Aging-associated transcriptome changes in liver sinusoidal endothelial cells.

PRJNA894478 | ENA

Freshly isolated rat liver sinusoidal endothelial cells and Kupffer cells, LC-MSMS

Liver sinusoidal endothelial cells (LSECs) and Kupffer cells (KCs) have important roles in liver homeostasis and host defense. Sharing the same microenvironment in the liver sinusoid, they form an effective scavenger cell system for removal of potentially harmful blood-borne substances. Unlike most ...

ORGANISM(S): Rattus norvegicus (Rat)

2020-11-11 | PXD012080 | Pride

Liver cells Macrophage Rat Immunity Endothelium

PROTEOMIC ANALYSIS OF DYSFUNCTIONAL LIVER SINUSOIDAL ENDOTHELIAL CELLS REVEALS SUBSTANTIAL DIFFERENCES IN MOST COMMON EXPERIMENTAL MODELS OF CHRONIC LIVER DISEASES.

Molecular markers of dedifferentiation of dysfunctional liver sinusoidal endothelial cells (LSEC), have not been fully elucidated. We aimed at deciphering the molecular profile of dysfunctional LSEC in different pathological scenarios. Flow cytometry was used to sort CD11bˉ/CD32b+ and CD11bˉ/CD3...

ORGANISM(S): Rattus norvegicus (Rat)

2023-10-24 | PXD040661 | Pride

Proteomics Liver sinusoidal endothelial cells Chronic liver disease Animal models Endothelial dysfunction

Transcriptome analysis of human sinusoidal endothelial cells, hepatocyte

We report the transcriptome human primary hepatocytes and liver sinusoidal endothelial cells. Hepatocytes were obtained from commercial sources. LSECs were isolated based on the coexpression of Tie2 and CD32b, te strategy of purification controlled by RNA-Seq. Comparison of the expression of the Ti...

ORGANISM(S): Homo sapiens

2015-01-01 | E-GEOD-43984 | biostudies-arrayexpress

Analysis of Scavenger-Receptor Type H deficient liver sinusoidal endothelial cells

PRJNA663314 | ENA

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