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MetabolomicsMacrosteatosis Cause Graft Failure Via Proliferative Arrest in Rats after Liver Transplantation
We created a rat model with macrosteatosis (MaS) liver via methionine-cholinedeficient food (MCD) diet and transplanted the MaS liver into normal rats, then the rats without any MaS will be set as control. In the whole process of surgeries, we procured the liver tissue samples in different time poin...
2023-11-20 | MTBLS4163 | MetaboLights
MetabolomicsFirst-in-class MKK4 inhibitors enhance liver regeneration and prevent liver failure

Diminished hepatocyte regeneration is a key feature of acute and chronic liver diseases and after extended liver resections, resulting in the inability to maintain or restore a sufficient functional liver mass. Therapies to restore hepatocyte regeneration are lacking, making liver transplantation...

2024-09-23 | MTBLS9434 | MetaboLights
TranscriptomicsGene expression profile in human orthotopic liver transplantation
We have studied the genes activated in human liver transplantation to identify potential target genes for the prevention or treatment of related injuries. In a first protocol, in order to evaluate the effect of Ischemia-Reperfusion Injury (IRI) on gene expression profile, we compared gene expressio...
ORGANISM(S): Homo sapiens 
2009-10-01 | E-GEOD-14951 | biostudies-arrayexpress
MetabolomicsMetabolomics Approach to Allograft Assessment in Liver Transplantation (part II)
Not available
ORGANISM(S): Homo sapiens 
ST000424 | MetabolomicsWorkbench
MetabolomicsMetabolomics of lung injury after allogeneic hematopoietic cell transplantation - Liver ICMS
Not available
ORGANISM(S): Mus musculus 
ST001453 | MetabolomicsWorkbench
TranscriptomicsMOLECULAR CHARACTERIZATION OF LIVER ALLOGRAFTS FROM OPERATIONALLY TOLERANT TRANSPLANT RECIPIENTS (Illumina)
In clinical organ transplantation complete cessation of immunosuppressive therapy can be successfully accomplished in selected recipients providing a proof-of-principle that allograft tolerance is attainable in humans. The intra-graft molecular pathways associated with human allograft tolerance, how...
ORGANISM(S): Homo sapiens 
2012-01-09 | E-GEOD-26625 | biostudies-arrayexpress
TranscriptomicsTranscriptome patterns for Acute Cellular Rejection in Recipients with Recurrent Hepatitis C after Liver Transplantation
The histological evaluation of liver via biopsy remains as the standard for the diagnosis of both acute cellular rejection (ACR) and recurrent hepatitis C (RHC) after liver transplantation. Nevertheless, it is often difficult to diagnose ACR in HCV-positive recipients because of common co-existing a...
ORGANISM(S): Homo sapiens 
2010-05-15 | E-GEOD-13440 | biostudies-arrayexpress
MetabolomicsMetabolomics of lung injury after allogeneic hematopoietic cell transplantation - Liver DI-FTMS
Not available
ORGANISM(S): Mus musculus 
ST001475 | MetabolomicsWorkbench
MetabolomicsMetabolomics of lung injury after allogeneic hematopoietic cell transplantation - Liver NMR HSQC
Not available
ORGANISM(S): Mus musculus 
ST001456 | MetabolomicsWorkbench
MetabolomicsMetabolomics of lung injury after allogeneic hematopoietic cell transplantation - Liver NMR 1D
Not available
ORGANISM(S): Mus musculus 
ST001455 | MetabolomicsWorkbench
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