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Recent drug discovery breakthroughs led to the approval of KRASG12C inhibitors in lung adenocarcinoma (LUAD). Unfortunately, clinical responses remain limited due to rapid resistance onset. Proteolysis-targeting chimeras (PROTACs) have emerged as promising alternatives to traditional inhibition. How...
ORGANISM(S): Mus musculus (Mouse) 
2026-05-13 | PXD058734 | Pride
Four lung adenocarcinoma patients with progression free survival (PFS) ranged from 2.13 to 14.5 months were recruited in the study. Paired PBMCs were collected before and after first regimen of PEM/CIS treatment for individualized analysis of membrane proteome profiles. The membrane protein fraction...
ORGANISM(S): Homo sapiens (Human) 
2018-01-02 | PXD006297 | Pride
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