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MetabolomicsA mitochondrial NADPH-cholesterol axis regulates extracellular vesicle biogenesis to support hematopoietic stem cell fate

Mitochondrial fatty acid oxidation (FAO) is essential for hematopoietic stem cell (HSC) self-renewal; however, the mechanism by which mitochondrial metabolism controls HSC fate remains unknown. Here, we show that within the hematopoietic lineage, HSCs have the largest mitochondrial NADPH pools, w...

2025-07-07 | MTBLS6401 | MetaboLights
UnknownAssociation of High-Risk Human Papillomavirus with Genital Tract Mucosal Immune Factors in HIV-Infected Women.
Not available
S-EPMC4715979 | biostudies-literature
UnknownOutcomes among ST-Elevation Myocardial Infarction (STEMI) patients with cardiogenic shock and COVID-19: A nationwide analysis.
Not available
S-EPMC9762040 | biostudies-literature
ProteomicsComprehensive single cell transcriptomics analysis of murine osteosarcoma uncovers Skp2 function in metastasis, genomic instability and immune activation and reveals additional target pathways
Osteosarcoma (OS) is the most common primary pediatric bone malignancy. One promising new therapeutic target is SKP2, encoding a substrate recognition factor of the SCF E3 ubiquitin ligase responsible for ubiquitination and proteasome degradation of substrate p27, thus driving cellular proliferation...
ORGANISM(S): Mus musculus (Mouse) 
2026-03-12 | PXD059605 | Pride
Osteosarcoma  skp2  single-cell rna-sequencing  tumor heterogeneity  immune infiltration  lineage plasticity 
UnknownConstruction and application of a protein interaction map for white spot syndrome virus (WSSV).
Not available
S-EPMC3879619 | biostudies-literature
UnknownPreoperative evaluation profile of patients undergoing arterial vascular surgery in a tertiary hospital.
Not available
S-EPMC11338055 | biostudies-literature
UnknownCOVID-19 in HIV-infected patients: A case series and literature review.
Not available
S-EPMC7753685 | biostudies-literature
UnknownGastric Lipomas: A Case Series and Review of the Literature.
Not available
S-EPMC10776135 | biostudies-literature
UnknownA pragmatic methodology to extract anesthetic and physiological data from the electronic health record.
Not available
S-EPMC10922302 | biostudies-literature
UnknownEpileptiform discharges, electrographic seizures, and electroclinical seizures during paediatric sevoflurane anaesthesia: a systematic review and proposal for standard definitions.
Not available
S-EPMC10925854 | biostudies-literature
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