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TranscriptomicsPemetrexed alters inflammatory profile in EA.hy 926 cells grown under low-folate conditions.
Pemetrexed is an antifolate drug used in the treatment of lung cancer. EA.hy 926 cells grown under low (Lo) and normal (Hi) folate conditions were treated with PMX. Microarray analysis was used to examine changes in gene expression due to PMX treatment. Hi and Lo cells were grown to confluence and m...
ORGANISM(S): Homo sapiens 
2012-10-03 | E-GEOD-31986 | biostudies-arrayexpress
TranscriptomicsMethotrexate activates aspects of inflammation in EA.hy 926 cells
Methotrexate (MTX) is an anti-folate drug used to treat inflammatory diseases such as rheumatoid arthritis. The changes induced by MTX were profiled within EA.hy 926 cells grown in normal (Hi) and low (Lo) folate. Several inflammatory genes were up regulated and several mitosis related genes were do...
ORGANISM(S): Homo sapiens 
2012-09-30 | E-GEOD-32008 | biostudies-arrayexpress
UnknownPrecursors and Effects of Self-reported Parental Reflective Functioning: Links to Parental Attachment Representations and Behavioral Sensitivity.
Not available
S-EPMC12628443 | biostudies-literature
UnknownDisease phenotype affects treatment of late-onset inflammatory bowel disease: Analysis of a large UK cohort.
Not available
S-EPMC13626234 | biostudies-literature
UnknownThe C5a receptor has a key role in immune complex glomerulonephritis in complement factor H-deficient mice.
Not available
S-EPMC3472160 | biostudies-literature
UnknownOverexpression of human 15(S)-lipoxygenase-1 in RAW macrophages leads to increased cholesterol mobilization and reverse cholesterol transport.
Not available
S-EPMC2759530 | biostudies-literature
UnknownTreatment preferences for preventive interventions for rheumatoid arthritis: protocol of a mixed methods case study for the Innovative Medicines Initiative PREFER project.
Not available
S-EPMC8039213 | biostudies-literature
TranscriptomicsLong non-coding RNAs regulate adipogenesis (Affymetrix)
Adipogenesis involves the regulation of hundreds of genes by several well-studied proteins, but the role of long, noncoding RNAs in this process has not been defined. We track the regulation of hundreds of lncRNAs during adipocyte differentiation, and find several that are essential for this proces...
ORGANISM(S): Mus musculus 
2013-02-15 | E-GEOD-29897 | biostudies-arrayexpress
GenomicsPregnancy-associated alterations in DNA methylation patterns of mammary epithelial stem cells [mRRBS]
Mammary gland development and luminal differentiation occur largely postnatally during puberty and pregnancy. We found that pregnancy had the most significant effects on stem cells, inducing a distinct epigenetic state that remained stable through life. Mammary glands were collected from mice at non...
ORGANISM(S): Mus musculus 
2015-01-22 | E-GEOD-54149 | biostudies-arrayexpress
UnknownOxygen-Donor Metalloligands Induce Slow Magnetization Relaxation in Zero Field for a Cobalt(II) Complex with {CoO4} Motif.
Not available
S-EPMC10966742 | biostudies-literature
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