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TranscriptomicsPemetrexed alters inflammatory profile in EA.hy 926 cells grown under low-folate conditions.
Pemetrexed is an antifolate drug used in the treatment of lung cancer. EA.hy 926 cells grown under low (Lo) and normal (Hi) folate conditions were treated with PMX. Microarray analysis was used to examine changes in gene expression due to PMX treatment. Hi and Lo cells were grown to confluence and m...
ORGANISM(S): Homo sapiens 
2012-10-03 | E-GEOD-31986 | biostudies-arrayexpress
TranscriptomicsMethotrexate activates aspects of inflammation in EA.hy 926 cells
Methotrexate (MTX) is an anti-folate drug used to treat inflammatory diseases such as rheumatoid arthritis. The changes induced by MTX were profiled within EA.hy 926 cells grown in normal (Hi) and low (Lo) folate. Several inflammatory genes were up regulated and several mitosis related genes were do...
ORGANISM(S): Homo sapiens 
2012-09-30 | E-GEOD-32008 | biostudies-arrayexpress
TranscriptomicsscRNA-seq of index-sorted myeloid and lymphoid progenitor cells and differentiated pDCs
Nine different cell types (common dendritic progenitor (CDP), pre-conventional dendritic cell (pre-cDC), common dendritic progenitor (CDPr, according to Rodrigues et al., but this population was flawed in sorting purity), Flt3+ CD11c+ Siglec-H+ CCR9-low B220-low progenitor cell (lo-lo), Flt3 + CD11c...
ORGANISM(S): Mus musculus 
2022-05-21 | E-MTAB-11752 | biostudies-arrayexpress
UnknownGlobal and regional accuracy of deep learning-based tumor segmentation from whole-body [<sup>18</sup>F]fluorodeoxyglucose PET/CT images.
Not available
S-EPMC12764704 | biostudies-literature
ProteomicsInhibition of human glioblastoma invasion and growth upon co-administration of a synergic miRNA pool actuated in vivo by nanocarriers
Although small interfering RNAs are being routinely used in the clinic, the therapeutic potential of oncogene co-regulation via multiple microRNAs (miRNAs) is still vastly underexplored. Here, the functional synergism of a pool of 11 miRNAs, which are involved in neural stem cell differentiation, wa...
ORGANISM(S): Homo sapiens (Human) 
2026-01-05 | PXD020335 | Pride
Nanoformulation Mirna Glioblastoma 
UnknownLiNbO3 Thin Films through a Sol-Gel/Spin-Coating Approach Using a Novel Heterobimetallic Lithium-Niobium Precursor.
Not available
S-EPMC10892834 | biostudies-literature
UnknownGrowth-inhibitory and antiangiogenic activity of the MEK inhibitor PD0325901 in malignant melanoma with or without BRAF mutations.
Not available
S-EPMC2713590 | biostudies-literature
UnknownA Low Temperature Growth of Cu2O Thin Films as Hole Transporting Material for Perovskite Solar Cells.
Not available
S-EPMC9657906 | biostudies-literature
UnknownInnate nuclear sensor IFI16 translocates into the cytoplasm during the early stage of in vitro human cytomegalovirus infection and is entrapped in the egressing virions during the late stage.
Not available
S-EPMC4054358 | biostudies-literature
TranscriptomicsHematopoietic Stem Cell Differentiation Regulated by a Single Ubiquitin Ligase: Substrate Complex
Hematopoietic stem cell (HSC) differentiation is regulated by cell-intrinsic and extrinsic cues. In addition to transcriptional regulation, post-translational regulation may also control HSC differentiation. To test this hypothesis, we visualized ubiquitin-regulated protein stability of a single tra...
ORGANISM(S): Mus musculus 
2010-03-07 | E-GEOD-19502 | biostudies-arrayexpress
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