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MetabolomicsAnalysis of Growth Phases of Enterotoxigenic Escherichia coli Reveals a Distinct Transition Phase before Entry into Early Stationary Phase with Shifts in Tryptophan, Fucose, and Putrescine Metabolism and Degradation of Neurotransmitter Precursors

Enterotoxigenic Escherichia coli (ETEC) is a major cause of diarrhea in children and adults in endemic areas. Gene regulation of ETEC during growth in vitro and in vivo needs to be further evaluated, and here we describe the full transcriptome and metabolome of ETEC dur...

2022-07-15 | MTBLS3540 | MetaboLights
TranscriptomicsTranscription profiling of SET-2 deletion and wild type yeast on sense and anti-sense arrays
The presence of Set2-mediated methylation of H3K36 (K36me) correlates with transcription frequency throughout the yeast genome. K36me targets the Rpd3S complex to deacetylate transcribed regions and suppress cryptic transcription initiation at certain genes. Here, using a genome-wide approach, we r...
ORGANISM(S): Saccharomyces cerevisiae 
2009-03-03 | E-TABM-265 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of fission yeast wild type and zinc regulatory null mutant grown in low zinc growth conditions
Transcription profile of low zinc growth condition in zinc regulatory null mutant
ORGANISM(S): Schizosaccharomyces pombe 
2008-02-22 | E-TABM-427 | biostudies-arrayexpress
TranscriptomicsRhabdoid Tumor: Gene Expression Clues to Pathogenesis and Potential Therapeutic Targets
Rhabdoid tumors (RT) are aggressive tumors characterized by genetic loss of SMARCB1 (SNF5, INI-1), a component of the SWI/SNF chromatin remodeling complex. No effective treatment is currently available. This study seeks to shed light on the SMARCB1-mediated pathogenesis of RT and to discover poten...
ORGANISM(S): Homo sapiens 
2010-03-09 | E-GEOD-11482 | biostudies-arrayexpress
ProteomicsEncystation deep proteome of Giardia duodenalis
Background: Cyst formation in parasitic protist Giardia duodenalis is critical to its transmission. Proteomic data is essential for the system-level understanding of the molecular mechanisms managing stage transition from a flagellated, binucleate trophozoite to a tetra-nucleate cyst. The current en...
ORGANISM(S): Giardia lamblia ATCC 50803 
2023-02-08 | PXD016863 | Pride
Proteomics Deep proteome Giardia Encystation 
ProteomicsGiardia duodenalis Assemblage B Proteome
Giardia duodenalis a species-complex of common gastrointestinal protists of major medical and veterinary importance. This complex is currently subclassifed as ‘Assemblages’, with Assemblage A and B infective to humans. To date, post-genomic proteomics are derived exclusively from Assemblage A, biasi...
ORGANISM(S): Giardia intestinalis assemblage B 
2018-07-03 | PXD007943 | Pride
Giardia Protozoa Label-free Giardia duodenalis Orbitrap Bottom-up proteomics Lc-ms/ms 
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