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Abstract: Altered expression of microRNAs (miRNAs) is associated with development and progression of various human cancers by regulating the translation of oncogenes and tumor suppressor genes. In colorectal cancer (CRC), these regulators complement the Vogelstein multi-step model of pathogenesis an...
ORGANISM(S): Homo sapiens 
To study the relationship between microRNAs and μ-opioid receptor (MOR) signaling, we examined microRNA expression after chronic morphine or fentanyl treatment in rat primary hippocampal neurons and in mouse hippocampus. Mouse cerebellum region was also tested as a negative control to eliminate mic...
ORGANISM(S): Homo sapiens 
Identification of micro-RNAs involved in regulating differential apoptosis and migration potential of human monocyte subsets Comparision between freshly isolated CD14++CD16- monocytes and CD14+CD16+ monocytes from healthy human blood
ORGANISM(S): Homo sapiens 
In the majority of colorectal cancers (CRC) under clinical suspicion for a hereditary cause, the disease-causing genetic factors are still to be discovered. In order to identify such genetic factors we stringently selected a discovery cohort of 41 CRC index patients with microsatellite-stable tumors...
ORGANISM(S): Homo sapiens 
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