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GenomicsMapping of transcription factor binding sites in mouse embryonic stem cells
Transcription factors and their specific interactions with targets are crucial in specifying gene expression programs. To gain insights into the transcriptional regulatory networks in embryonic stem cells, we use chromatin immunoprecipitation coupled to ultra-high-throughput DNA sequencing (ChIP-seq...
ORGANISM(S): Mus musculus 
2008-06-12 | E-GEOD-11431 | biostudies-arrayexpress
TranscriptomicsGenome-Wide Analysis of Somatic Copy Number Alterations and Gene Expression in Metastatic Melanoma
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2011-04-07 | E-GEOD-23056 | biostudies-arrayexpress
UnknownEffectiveness of an ocular adhesive polyhedral oligomeric silsesquioxane hybrid thermo-responsive FK506 hydrogel in a murine model of dry eye.
Not available
S-EPMC8586264 | biostudies-literature
TranscriptomicsGeneration of isogenic pluripotent stem cells differing exclusively at two early onset Parkinson point mutations
This SuperSeries is composed of the following subset Series: GSE29772: CNV analysis for Generation of isogenic pluripotent stem cells differing exclusively at two early onset Parkinson point mutations GSE29773: Gene Expression Data for Generation of isogenic pluripotent stem cells differing exclusiv...
ORGANISM(S): Homo sapiens 
2011-07-25 | E-GEOD-29774 | biostudies-arrayexpress
GenomicsPCGP Ph-like ALL
Background: BCR-ABL1-like, or Ph-like acute lymphoblastic leukemia is characterized by a gene expression profile similar to BCR-ABL1 positive ALL, genetic alterations of lymphoid transcription factor genes, and poor outcome. Sequencing of small numbers of Ph-like ALL cases has identified genetic alt...
EGAS00001000654 | EGA
TranscriptomicsTranscription profiling of mouse hypomorphic for ATG16L1 (implicated in Crohns disease) protein expression reveals a key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells
Susceptibility to Crohn's disease, a complex inflammatory disease involving the small intestine, is controlled by over 30 loci. One Crohn's disease risk allele is in ATG16L1, a gene homologous to the essential yeast autophagy gene ATG16 (ref. 2). It is not known how ATG16L1 or autophagy contributes ...
ORGANISM(S): Mus musculus 
2008-11-15 | E-GEOD-13512 | biostudies-arrayexpress
MetabolomicsImpact of myocardial reperfusion on human plasma lipidome
The primary aim of the study is to investigate the temporal changes in plasma lipidome before and after reperfusion in patients with ST-segment elevation myocardial infarction (STEMI) and their association with myocardial injury. We found that 56% of the identified lipid species were significantly a...
2022-02-07 | MTBLS3839 | MetaboLights
TranscriptomicsLongitudinal scRNAseq profiling of memory B cells in mRNA vaccinated individuals post BA.1-breakthrough infection
Memory B cells play a fundamental role in host defenses against viruses. This dataset aimed at understanding the recruitment and remodeling of the memory B cell repertoire in the context of BA.1-breakthrough infection in BNT162b2 mRNA vaccinated individuals. All four donors enrolled in the study had...
ORGANISM(S): Homo sapiens 
2023-08-15 | E-MTAB-12651 | biostudies-arrayexpress
TranscriptomicsLongitudinal scRNAseq profiling of memory B cells in severe COVID19 patients
Memory B cells play a fundamental role in host defences against viruses. This dataset aimed at understanding their maturation and stability in the context of SARS-CoV-2 infection and consist of a longitudinal single-cell and repertoire profiling of the B cell response up to six months in four severe...
ORGANISM(S): Homo sapiens 
2021-01-31 | E-MTAB-9995 | biostudies-arrayexpress
GenomicsPCGP Ph-likeALL RNASeq - samples
DATA FILES FOR SJPhLike-RNASeq
EGAD00001001016 | EGA
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