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ProteomicsUrinary Glycosylated IGF2 peptides in association with CKD
Chronic kidney disease (CKD) is prevalent in 10% of world’s adult population, with Estimated Glomerular filtration rate (eGFR) and albuminuria employed in diagnosis. Role of protein glycosylation in causal mechanisms of CKD progression is largely unknown. Aim of this study was to identify urinary O-...
ORGANISM(S): Homo sapiens (Human) 
2023-05-10 | PXD039829 | Pride
Ckd  egfr  post translational modifications  ptms  glycosylation  urine  peptidomics  glyco-peptide  igf2 
ProteomicsInvestigation of the human-gut-kidney axis by fecal proteomics, highlights molecular mechanisms affected in the later stages of CKD
The interplay of gut microbiota with the kidney system, characteristic to reduced kidney function and increased concentrations of urea in gut; in turn increases bacterial urease activity and generation of uremic toxins. Knowledge on these underlying bidirectional molecular mechanisms is nevertheless...
ORGANISM(S): Homo sapiens (Human) 
2025-06-02 | PXD048778 | Pride
Butyrate Ckd Inflammation Gut Bioinformatics Fecal Proteomics Lc-ms/ms 
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