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ProteomicsLineage-specific Protein Interactomes of the Hox Transcription Factor Ubx revealed by Close-Proximity Protein Biotinylation
Cell type diversity is controlled by transcription factors (TFs), which regulate specific yet flexible gene expression programs depending on the cellular environment. However, how sets of TFs work together to promote such diversity with high precision is still unknown. We used the Hox TF Ultrabithor...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2020-04-22 | PXD014481 | Pride
Close-proximity biotinylation Transcription Close-proximity partners Ubx Ppi Drosophila Interaction Interactome Bioid Ultrabithorax Proteomics Development Hox 
TranscriptomicsTranscription profiling of Drosophila embryos at stages 11 and 12 to identify genes downstream of Hox
Identification of Hox gene downstream genes at embryonic stages 11 and 12

Functional diversification of body parts is dependent on the formation of specialized structures along the various body axes. In animals, region-specific morphogenesis along the anterior-posterior axis is controlled by ...
ORGANISM(S): Drosophila melanogaster 
2008-04-09 | E-MEXP-879 | biostudies-arrayexpress
TranscriptomicsThe Hox gene Abd-B controls stem cell niche function in the Drosophila testis
Stem cells reside in a specialized microenvironment, called niche, which provides essential signals controlling stem cell behavior. Proper niche architecture is a key for normal stem cell function, yet only few upstream regulators are known. Here we report that the Hox transcription factor Abd-B, ac...
ORGANISM(S): Drosophila melanogaster 
2013-12-30 | E-GEOD-53709 | biostudies-arrayexpress
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