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TranscriptomicsPAO1-Lon-ciprofloxacin
Microarray experiments were preformed comparing the effect of sub-inhibitory concentrations of ciprofloxacin on five independent cultures of PAO1 and the PAO1 Lon mutant
ORGANISM(S): Pseudomonas aeruginosa PAO1 
2012-03-25 | E-MTAB-1000 | biostudies-arrayexpress
ProteomicsIdentification of substrates of LarA-activated Lon protease and Identification of Lon protease interactome
With this analysis we aim to identify proteins that are substrates of LarA-activated Lon protease in Caulobacter crescentus. We will compare samples of wild type cells either harboring an empty vector (vector control, VC) or overexpressing 3xFLAG-tagged LarA (F-LarA). Based on our previous data we h...
ORGANISM(S): Caulobacter crescentus (strain NA1000 / CB15N) 
2023-10-25 | PXD036514 | Pride
Caulobacter crescentus Lon activity regulator Lara Lon protease 
GenomicsRNA-seq and ChIP-seq for Lon
RNA-seq and ChIP-seq for Lon
PRJNA564989 | ENA
TranscriptomicsRNA-seq and ChIP-seq for Lon
Lon protease plays vital roles in many biological processes in Pseudomonas syringae, including type III secretion systems (T3SS), transcription regulation, protein synthesis and energy metabolism. Lon also functions as a transcriptional regulator in other bacterial species (e.g., Escherichia coli an...
ORGANISM(S): Pseudomonas savastanoi pv. phaseolicola 1448A 
2020-06-30 | GSE137273 | GEO
GenomicsChip-seq analysis of hrpRSL and Lon in Pseudomonas syringas
Pseudomonas syringae uses HrpRSL to regulate the expression of type III secretion system (T3SS) genes and bacterial virulence. However, the molecular mechanism and the regulons of HrpRSL have yet to be fully elucidated. Here, we performed chromatin immunoprecipitation followed by high-throughput DNA...
ORGANISM(S): Pseudomonas syringae 
2015-12-31 | E-GEOD-65437 | biostudies-arrayexpress
ProteomicsPrkA regulates Bacillus subtilis sporulation through a Lon protease activity
In Bacillus subtilis, sporulation is a sequential and highly regulated process. Phosphorylation events by Histidine or Serine/Threonine kinases are key points in this regulation. PrkA has been proposed to be an essential Serine kinase for the initiation of sporulation but its kinase activity has not...
ORGANISM(S): Bacillus subtilis subsp. subtilis str. 168 
2022-10-15 | PXD032931 | Pride
Atpase Prka Lon protease Sporulation Phosphorylation Bacillus subtilis 
ProteomicsHaloferax volcanii proteome turn-over analysis of a LonB mutant and co-IP results with anti-LonB
The proteome turnover was examined in a conditional LonB mutant (HVLON3) of the model euryarchaeon H. volcanii under reduced (- trp) and nearly physiological (+ trp) LonB levels. HVLON3 was initially grown in minimal medium containing 14NH4Cl as nitrogen source in absence of trp and then switched to...
ORGANISM(S): Haloferax Volcanii Ds2 
2018-02-19 | PXD007061 | JPOST Repository
TranscriptomicsE. coli BW25113 K-12 hfq vs. wild-type persister
Persisters are cells which evade stresses like antibiotics and which are characterized by reduced metabolism and a lack of genetic alterations required to achieve this state. We showed previously that MqsR and MqsA of Escherichia coli are a toxin-antitoxin pair that influence cell physiology (e.g.,...
ORGANISM(S): Escherichia coli 
2009-11-07 | E-GEOD-18852 | biostudies-arrayexpress
UnknownMitochondrial Lon is over-expressed in high-grade gliomas, and mediates hypoxic adaptation: potential role of Lon as a therapeutic target in glioma.
Not available
S-EPMC5340227 | biostudies-literature
UnknownMitochondrial Lon regulates apoptosis through the association with Hsp60-mtHsp70 complex.
Not available
S-EPMC4669791 | biostudies-literature
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